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β-Sitosterol Circumvents Obesity Induced Inflammation and Insulin Resistance by down-Regulating IKKβ/NF-κB and JNK Signaling Pathway in Adipocytes of Type 2 Diabetic Rats.
Jayaraman S, Devarajan N, Rajagopal P, Babu S, Ganesan SK, Veeraraghavan VP, Palanisamy CP, Cui B, Periyasamy V, Chandrasekar K. Jayaraman S, et al. Among authors: chandrasekar k. Molecules. 2021 Apr 6;26(7):2101. doi: 10.3390/molecules26072101. Molecules. 2021. PMID: 33917607 Free PMC article.
JNK1 and JNK3 play a significant role in both neuronal apoptosis and necrosis. Evaluation based on in vitro approach using tert-butylhydroperoxide induced oxidative stress in neuro-2A cells and perturbation through 3-aminobenzamide.
Muthaiah VPK, Michael FM, Palaniappan T, Rajan SS, Chandrasekar K, Venkatachalam S. Muthaiah VPK, et al. Among authors: chandrasekar k. Toxicol In Vitro. 2017 Jun;41:168-178. doi: 10.1016/j.tiv.2017.02.015. Epub 2017 Feb 28. Toxicol In Vitro. 2017. PMID: 28257805
Contusive spinal cord injury up regulates mu-opioid receptor (mor) gene expression in the brain and down regulates its expression in the spinal cord: possible implications in spinal cord injury research.
Michael FM, Mohapatra AN, Venkitasamy L, Chandrasekar K, Seldon T, Venkatachalam S. Michael FM, et al. Among authors: chandrasekar k. Neurol Res. 2015 Sep;37(9):788-96. doi: 10.1179/1743132815Y.0000000057. Epub 2015 Jun 3. Neurol Res. 2015. PMID: 26039701