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Page 1
Overcoming hypoxia-induced resistance of pancreatic and lung tumor cells by disrupting the PERK-NRF2-HIF-axis.
Cell Death Dis. 2021 Jan 13;12(1):82. doi: 10.1038/s41419-020-03319-7.
Cell Death Dis. 2021.
PMID: 33441543
Free PMC article.
Depletion of HIF-1α by Inducible Cre/loxP Increases the Sensitivity of Cultured Murine Hepatocytes to Ionizing Radiation in Hypoxia.
Hamidi A, Wolf A, Dueva R, Kaufmann M, Göpelt K, Iliakis G, Metzen E.
Hamidi A, et al. Among authors: gopelt k.
Cells. 2022 May 18;11(10):1671. doi: 10.3390/cells11101671.
Cells. 2022.
PMID: 35626708
Free PMC article.
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Autophagy induced by ionizing radiation promotes cell death over survival in human colorectal cancer cells.
Classen F, Kranz P, Riffkin H, Pompsch M, Wolf A, Göpelt K, Baumann M, Baumann J, Brockmeier U, Metzen E.
Classen F, et al. Among authors: gopelt k.
Exp Cell Res. 2019 Jan 1;374(1):29-37. doi: 10.1016/j.yexcr.2018.11.004. Epub 2018 Nov 6.
Exp Cell Res. 2019.
PMID: 30412717
Free article.
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In oxygen-deprived tumor cells ERp57 provides radioprotection and ensures proliferation via c-Myc, PLK1 and the AKT pathway.
Ocklenburg T, Neumann F, Wolf A, Vogel J, Göpelt K, Baumann M, Baumann J, Kranz P, Metzen E, Brockmeier U.
Ocklenburg T, et al. Among authors: gopelt k.
Sci Rep. 2021 Mar 30;11(1):7199. doi: 10.1038/s41598-021-86658-5.
Sci Rep. 2021.
PMID: 33785835
Free PMC article.
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Tumor cells rely on the thiol oxidoreductase PDI for PERK signaling in order to survive ER stress.
Kranz P, Sänger C, Wolf A, Baumann J, Metzen E, Baumann M, Göpelt K, Brockmeier U.
Kranz P, et al. Among authors: gopelt k.
Sci Rep. 2020 Sep 17;10(1):15299. doi: 10.1038/s41598-020-72259-1.
Sci Rep. 2020.
PMID: 32943707
Free PMC article.
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