A functional family-wide screening of SP/KLF proteins identifies a subset of suppressors of KRAS-mediated cell growth.
Fernandez-Zapico ME, Lomberk GA, Tsuji S, DeMars CJ, Bardsley MR, Lin YH, Almada LL, Han JJ, Mukhopadhyay D, Ordog T, Buttar NS, Urrutia R.
Fernandez-Zapico ME, et al.
Biochem J. 2011 Apr 15;435(2):529-37. doi: 10.1042/BJ20100773.
Biochem J. 2011.
PMID: 21171965
Free PMC article.
SP/KLF (Specificity protein/Kruppel-like factor) transcription factors comprise an emerging group of proteins that may behave as tumour suppressors. Incidentally, many cancers that display alterations in certain KLF proteins are also associated with a high incidence of KRA …
SP/KLF (Specificity protein/Kruppel-like factor) transcription factors comprise an emerging group of proteins that may behave as tumo …