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Showing results for kimberley leads
Search for Kimberley Lears instead (1 results)
The co-evolution of the genome and epigenome in colorectal cancer.
Heide T, Househam J, Cresswell GD, Spiteri I, Lynn C, Mossner M, Kimberley C, Fernandez-Mateos J, Chen B, Zapata L, James C, Barozzi I, Chkhaidze K, Nichol D, Gunasri V, Berner A, Schmidt M, Lakatos E, Baker AM, Costa H, Mitchinson M, Piazza R, Jansen M, Caravagna G, Ramazzotti D, Shibata D, Bridgewater J, Rodriguez-Justo M, Magnani L, Graham TA, Sottoriva A. Heide T, et al. Nature. 2022 Nov;611(7937):733-743. doi: 10.1038/s41586-022-05202-1. Epub 2022 Oct 26. Nature. 2022. PMID: 36289335 Free PMC article.
Colorectal malignancies are a leading cause of cancer-related death(1 )and have undergone extensive genomic study(2,3). ...
Colorectal malignancies are a leading cause of cancer-related death(1 )and have undergone extensive genomic study(2,3). ...
Programmatic Precision Oncology Decision Support for Patients With Gastrointestinal Cancer.
Keller RB, Mazor T, Sholl L, Aguirre AJ, Singh H, Sethi N, Bass A, Nagaraja AK, Brais LK, Hill E, Hennessey C, Cusick M, Del Vecchio Fitz C, Zwiesler Z, Siegel E, Ovalle A, Trukhanov P, Hansel J, Shapiro GI, Abrams TA, Biller LH, Chan JA, Cleary JM, Corsello SM, Enzinger AC, Enzinger PC, Mayer RJ, McCleary NJ, Meyerhardt JA, Ng K, Patel AK, Perez KJ, Rahma OE, Rubinson DA, Wisch JS, Yurgelun MB, Hassett MJ, MacConaill L, Schrag D, Cerami E, Wolpin BM, Nowak JA, Giannakis M. Keller RB, et al. JCO Precis Oncol. 2023 Jan;7:e2200342. doi: 10.1200/PO.22.00342. JCO Precis Oncol. 2023. PMID: 36634297 Free PMC article.
We recommended 1 precision medicine clinical trial for 80% (406 of 506) of patients, leading to 24 enrollments. We recommended on-label and off-label targeted therapies for 6% (28 of 506) and 25% (125 of 506) of patients, respectively. ...
We recommended 1 precision medicine clinical trial for 80% (406 of 506) of patients, leading to 24 enrollments. We recommended on-lab …
The follow up of complex infants in an aerodigestive clinic.
Kaspy KR, Burg G, Garrison AP, Miller CK, Pentiuk S, Smith MM, Benscoter D. Kaspy KR, et al. Paediatr Respir Rev. 2022 Dec;44:3-10. doi: 10.1016/j.prrv.2022.06.002. Epub 2022 Jul 4. Paediatr Respir Rev. 2022. PMID: 36411238 Review.
The team approach central to aerodigestive clinics offers a comprehensive diagnostic workup and unified management plan through consolidated interdisciplinary clinics, combined endoscopic procedures, and regular team discussions, leading to improved resource utilization an …
The team approach central to aerodigestive clinics offers a comprehensive diagnostic workup and unified management plan through consolidated …
Targeted Vagus Nerve Stimulation for Rehabilitation After Stroke.
Engineer ND, Kimberley TJ, Prudente CN, Dawson J, Tarver WB, Hays SA. Engineer ND, et al. Front Neurosci. 2019 Mar 29;13:280. doi: 10.3389/fnins.2019.00280. eCollection 2019. Front Neurosci. 2019. PMID: 30983963 Free PMC article. Review.
Stroke is a leading cause of disability worldwide, and in approximately 60% of individuals, upper limb deficits persist 6 months after stroke. ...
Stroke is a leading cause of disability worldwide, and in approximately 60% of individuals, upper limb deficits persist 6 months afte …
Cerebral perturbations during exercise in hypoxia.
Verges S, Rupp T, Jubeau M, Wuyam B, Esteve F, Levy P, Perrey S, Millet GY. Verges S, et al. Am J Physiol Regul Integr Comp Physiol. 2012 Apr 15;302(8):R903-16. doi: 10.1152/ajpregu.00555.2011. Epub 2012 Feb 8. Am J Physiol Regul Integr Comp Physiol. 2012. PMID: 22319046 Free article. Review.
This accelerated development of muscle fatigue in moderate hypoxia may be responsible for increased inhibitory afferent signals to the central nervous system leading to impaired central drive. In severe hypoxia (arterial O(2) saturation <70-75%), cerebral hypoxia per se …
This accelerated development of muscle fatigue in moderate hypoxia may be responsible for increased inhibitory afferent signals to the centr …
Bridging the Gap between Gut Microbial Dysbiosis and Cardiovascular Diseases.
Lau K, Srivatsav V, Rizwan A, Nashed A, Liu R, Shen R, Akhtar M. Lau K, et al. Nutrients. 2017 Aug 10;9(8):859. doi: 10.3390/nu9080859. Nutrients. 2017. PMID: 28796176 Free PMC article. Review.
Imbalances in host-microbial interaction impair homeostatic mechanisms that regulate health and can activate multiple pathways leading to CVD risk factor progression. Dysbiosis has been implicated in the development of atherosclerosis through metabolism-independent and met …
Imbalances in host-microbial interaction impair homeostatic mechanisms that regulate health and can activate multiple pathways leading …
Current Models of Fatty Liver Disease; New Insights, Therapeutic Targets and Interventions.
Jonscher KR, Bruce KD. Jonscher KR, et al. Adv Exp Med Biol. 2019;1134:33-58. doi: 10.1007/978-3-030-12668-1_3. Adv Exp Med Biol. 2019. PMID: 30919331 Review.
NAFLD is currently the most prevalent chronic liver disease worldwide, with a global prevalence of 25%, and is soon projected to be the leading cause for liver transplantation in the US. Alarmingly, few effective pharmacotherapeutic approaches are currently available to bl …
NAFLD is currently the most prevalent chronic liver disease worldwide, with a global prevalence of 25%, and is soon projected to be the l …
Reactive oxygen species and NADPH oxidase 4 involvement in osteoarthritis.
Drevet S, Gavazzi G, Grange L, Dupuy C, Lardy B. Drevet S, et al. Exp Gerontol. 2018 Oct 1;111:107-117. doi: 10.1016/j.exger.2018.07.007. Epub 2018 Jul 17. Exp Gerontol. 2018. PMID: 30012342 Review.
Disruption of the cartilage homeostasis in favor of catabolism leads to cartilage destruction. ROS-macromolecular-induced damage is significantly greater in OA cartilage and OA is described as low-grade chronic systemic inflammation. ...Age-related advanced glycation end p …
Disruption of the cartilage homeostasis in favor of catabolism leads to cartilage destruction. ROS-macromolecular-induced damage is s …
Adult obesity management in New Zealand general practice: a review.
Norman K, Chepulis L, Burrows L, Lawrenson R. Norman K, et al. J Prim Health Care. 2021 Sep;13(3):249-259. doi: 10.1071/HC20135. J Prim Health Care. 2021. PMID: 34588109 Review.
INTRODUCTION Obesity is an important issue that leads to further health complications, increases the strain on the national health system and lowers quality of life. ...
INTRODUCTION Obesity is an important issue that leads to further health complications, increases the strain on the national health sy …
Measuring verticality perception after stroke: why and how?
Pérennou D, Piscicelli C, Barbieri G, Jaeger M, Marquer A, Barra J. Pérennou D, et al. Neurophysiol Clin. 2014 Jan;44(1):25-32. doi: 10.1016/j.neucli.2013.10.131. Epub 2013 Nov 1. Neurophysiol Clin. 2014. PMID: 24502902 Review.
Measuring the postural vertical with the wheel paradigm has allowed elucidating the mechanisms of lateropulsion, leading or not to a pushing. Schematically, patients with a hemispheric stroke align their erect posture with an erroneous reference of verticality, tilted to t …
Measuring the postural vertical with the wheel paradigm has allowed elucidating the mechanisms of lateropulsion, leading or not to a …
37 results