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Advanced Dome cellulose/alginate/chitosan composite matrix design with gastric and intestinal co-targeting capacities.
Razali S, Bose A, Benetti C, Chong PW, Miller M, Colombo P, Colombo G, Wong TW. Razali S, et al. Int J Pharm. 2022 Nov 25;628:122226. doi: 10.1016/j.ijpharm.2022.122226. Epub 2022 Oct 1. Int J Pharm. 2022. PMID: 36191818
With reference to the caffeine module, the detachment of melatonin module facilitated its gastrointestinal transit as a reduced size matrix, with majority of caffeine delivered in colon. The dual site-targeted and -release Dome matrix is applicable as reference oral carrie …
With reference to the caffeine module, the detachment of melatonin module facilitated its gastrointestinal transit as a reduced size matrix, …
Design of multi-particulate "Dome matrix" with sustained-release melatonin and delayed-release caffeine for jet lag treatment.
Razali S, Bose A, Chong PW, Benetti C, Colombo P, Wong TW. Razali S, et al. Int J Pharm. 2020 Sep 25;587:119618. doi: 10.1016/j.ijpharm.2020.119618. Epub 2020 Jul 14. Int J Pharm. 2020. PMID: 32673769
Admixing of cushioning agent high viscosity hydroxypropylmethylcellulose and high viscosity ethylcellulose (9:1 wt ratio) with coat-free caffeine loaded particulates introduced delayed-release response via hydroxypropylmethylcellulose swelled in early dissolution phase and ethylc …
Admixing of cushioning agent high viscosity hydroxypropylmethylcellulose and high viscosity ethylcellulose (9:1 wt ratio) with coat-free caf …