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Showing results for kevin coupling
Search for Kevin Couling instead (1 results)
Efficient generation of lower induced motor neurons by coupling Ngn2 expression with developmental cues.
Limone F, Guerra San Juan I, Mitchell JM, Smith JLM, Raghunathan K, Meyer D, Ghosh SD, Couto A, Klim JR, Joseph BJ, Gold J, Mello CJ, Nemesh J, Smith BM, Verhage M, McCarroll SA, Pietiläinen O, Nehme R, Eggan K. Limone F, et al. Cell Rep. 2023 Jan 31;42(1):111896. doi: 10.1016/j.celrep.2022.111896. Epub 2023 Jan 2. Cell Rep. 2023. PMID: 36596304 Free PMC article.
Current protocols either direct neuronal differentiation with small molecules or use transcription-factor-mediated programming. In this study, we couple overexpression of transcription factor Neurogenin2 (Ngn2) with small molecule patterning to differentiate hPSCs into low …
Current protocols either direct neuronal differentiation with small molecules or use transcription-factor-mediated programming. In this stud …
Henry's Law.
Avishay DM, Tenny KM. Avishay DM, et al. 2023 Jan 29. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 Jan 29. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 31335021 Free Books & Documents.
A subspecialty within occupational medicine, the challenge of aerospace medicine lies in safeguarding the health of individuals who work in a dynamic atmosphere of lowering pressure and oxygen content, coupled with increasing altitude. It is essential to comprehend the phy …
A subspecialty within occupational medicine, the challenge of aerospace medicine lies in safeguarding the health of individuals who work in …
Analysis of patients without and with an initial triple-negative breast cancer diagnosis in the phase 3 randomized ASCENT study of sacituzumab govitecan in metastatic triple-negative breast cancer.
O'Shaughnessy J, Brufsky A, Rugo HS, Tolaney SM, Punie K, Sardesai S, Hamilton E, Loirat D, Traina T, Leon-Ferre R, Hurvitz SA, Kalinsky K, Bardia A, Henry S, Mayer I, Zhu Y, Phan S, Cortés J. O'Shaughnessy J, et al. Breast Cancer Res Treat. 2022 Sep;195(2):127-139. doi: 10.1007/s10549-022-06602-7. Epub 2022 May 11. Breast Cancer Res Treat. 2022. PMID: 35545724 Free PMC article. Clinical Trial.
PURPOSE: Sacituzumab govitecan (SG) is an antibody-drug conjugate composed of an anti-Trop-2 antibody coupled to SN-38 via a proprietary hydrolyzable linker. In the ASCENT study, SG improved survival versus single-agent treatment of physician's choice (TPC) in pre-treated …
PURPOSE: Sacituzumab govitecan (SG) is an antibody-drug conjugate composed of an anti-Trop-2 antibody coupled to SN-38 via a propriet …
Goal-Directed Therapy for Cardiac Surgery.
Lobdell KW, Chatterjee S, Sander M. Lobdell KW, et al. Crit Care Clin. 2020 Oct;36(4):653-662. doi: 10.1016/j.ccc.2020.06.004. Epub 2020 Aug 12. Crit Care Clin. 2020. PMID: 32892819 Review.
Goal-directed therapy couples therapeutic interventions with physiologic and metabolic targets to mitigate a patient's modifiable risks for death and complications. ...
Goal-directed therapy couples therapeutic interventions with physiologic and metabolic targets to mitigate a patient's modifiable ris …
25th Annual Computational Neuroscience Meeting: CNS-2016.
Sharpee TO, Destexhe A, Kawato M, Sekulić V, Skinner FK, Wójcik DK, Chintaluri C, Cserpán D, Somogyvári Z, Kim JK, Kilpatrick ZP, Bennett MR, Josić K, Elices I, Arroyo D, Levi R, Rodriguez FB, Varona P, Hwang E, Kim B, Han HB, Kim T, McKenna JT, Brown RE, McCarley RW, Choi JH, Rankin J, Popp PO, Rinzel J, Tabas A, Rupp A, Balaguer-Ballester E, Maturana MI, Grayden DB, Cloherty SL, Kameneva T, Ibbotson MR, Meffin H, Koren V, Lochmann T, Dragoi V, Obermayer K, Psarrou M, Schilstra M, Davey N, Torben-Nielsen B, Steuber V, Ju H, Yu J, Hines ML, Chen L, Yu Y, Kim J, Leahy W, Shlizerman E, Birgiolas J, Gerkin RC, Crook SM, Viriyopase A, Memmesheimer RM, Gielen S, Dabaghian Y, DeVito J, Perotti L, Kim AJ, Fenk LM, Cheng C, Maimon G, Zhao C, Widmer Y, Sprecher S, Senn W, Halnes G, Mäki-Marttunen T, Keller D, Pettersen KH, Andreassen OA, Einevoll GT, Yamada Y, Steyn-Ross ML, Alistair Steyn-Ross D, Mejias JF, Murray JD, Kennedy H, Wang XJ, Kruscha A, Grewe J, Benda J, Lindner B, Badel L, Ohta K, Tsuchimoto Y, Kazama H, Kahng B, Tam ND, Pollonini L, Zouridakis G, Soh J, Kim D, Yoo M, Palmer SE, Culmone V, Bojak I, Ferrario A, Merrison-Hort R, Borisyuk R, Kim CS, Tezuka T, Joo P, Rho YA, Burt… See abstract for full author list ➔ Sharpee TO, et al. BMC Neurosci. 2016 Aug 18;17 Suppl 1(Suppl 1):54. doi: 10.1186/s12868-016-0283-6. BMC Neurosci. 2016. PMID: 27534393 Free PMC article.
Fink P163 Neuronal diversity in structure and function: cross-validation of anatomical and physiological classification of retinal ganglion cells in the mouse Jinseop S. Kim, Shang Mu, Kevin L. Briggman, H. Sebastian Seung, the EyeWirers P164 Analysis and modelling of tran …
Fink P163 Neuronal diversity in structure and function: cross-validation of anatomical and physiological classification of retinal ganglion …
Gas-phase infrared spectroscopy of glycans and glycoconjugates.
Greis K, Kirschbaum C, von Helden G, Pagel K. Greis K, et al. Curr Opin Struct Biol. 2022 Feb;72:194-202. doi: 10.1016/j.sbi.2021.11.006. Epub 2021 Dec 21. Curr Opin Struct Biol. 2022. PMID: 34952241 Review.
Standard workflows for glycan analysis are based on mass spectrometry, often coupled with separation techniques such as liquid chromatography and ion mobility spectrometry. ...
Standard workflows for glycan analysis are based on mass spectrometry, often coupled with separation techniques such as liquid chroma …
Physiologic, Pathologic, and Therapeutic Paracrine Modulation of Cardiac Excitation-Contraction Coupling.
Mayourian J, Ceholski DK, Gonzalez DM, Cashman TJ, Sahoo S, Hajjar RJ, Costa KD. Mayourian J, et al. Circ Res. 2018 Jan 5;122(1):167-183. doi: 10.1161/CIRCRESAHA.117.311589. Circ Res. 2018. PMID: 29301848 Free PMC article. Review.
Cardiac excitation-contraction coupling (ECC) is the orchestrated process of initial myocyte electrical excitation, which leads to calcium entry, intracellular trafficking, and subsequent sarcomere shortening and myofibrillar contraction. ...
Cardiac excitation-contraction coupling (ECC) is the orchestrated process of initial myocyte electrical excitation, which leads to ca …
Phase-Amplitude Coupling of the Electroencephalogram in the Auditory Cortex in Schizophrenia.
Hirano S, Nakhnikian A, Hirano Y, Oribe N, Kanba S, Onitsuka T, Levin M, Spencer KM. Hirano S, et al. Biol Psychiatry Cogn Neurosci Neuroimaging. 2018 Jan;3(1):69-76. doi: 10.1016/j.bpsc.2017.09.001. Epub 2017 Sep 13. Biol Psychiatry Cogn Neurosci Neuroimaging. 2018. PMID: 29397081
While neural oscillations associated with particular circuits in schizophrenia (SZ) are impaired, few studies have examined cross-frequency interactions. Here we examined phase-amplitude coupling (PAC) in the electroencephalograms of individuals with SZ and healthy control …
While neural oscillations associated with particular circuits in schizophrenia (SZ) are impaired, few studies have examined cross-frequency …
The genetics of neurodevelopmental disease.
Mitchell KJ. Mitchell KJ. Curr Opin Neurobiol. 2011 Feb;21(1):197-203. doi: 10.1016/j.conb.2010.08.009. Epub 2010 Sep 9. Curr Opin Neurobiol. 2011. PMID: 20832285 Review.
The term neurodevelopmental disorder encompasses a wide range of diseases, including recognizably distinct syndromes known to be caused by very rare mutations in specific genes or chromosomal loci, and also much more common disorders such as schizophrenia, autism spectrum disorde …
The term neurodevelopmental disorder encompasses a wide range of diseases, including recognizably distinct syndromes known to be caused by v …
Advanced endoscopic technologies.
Reavis KM, Melvin WS. Reavis KM, et al. Surg Endosc. 2008 Jun;22(6):1533-46. doi: 10.1007/s00464-008-9831-1. Epub 2008 Apr 10. Surg Endosc. 2008. PMID: 18401657 Review.
Initially, endoscopy relied on rigid telescopes, direct visualization, and dangerously exothermic sources of illumination. The introduction of fiber optics, charge-coupled-device cameras, and increasingly efficient light sources has enabled researchers to investigate areas …
Initially, endoscopy relied on rigid telescopes, direct visualization, and dangerously exothermic sources of illumination. The introduction …
303 results