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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2003 1
2004 1
2005 1
2007 1
2008 1
2010 2
2016 2
2018 2
2019 3
2020 1
2021 6
2023 3
2024 1

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23 results

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Page 1
Discovery of MK-8768, a Potent and Selective mGluR2 Negative Allosteric Modulator.
Rudd MT, Manley PJ, Hanney B, Meng Z, Shu Y, de Leon P, Frie JL, Han Y, Wai JM, Yang ZQ, Perkins JJ, Hurzy DM, Manikowski JJ, Zhu H, Bungard CJ, Converso A, Meissner RS, Cosden ML, Hayashi I, Ma L, O'Brien J, Uebele VN, Schachter JB, Bhandari N, Ward GJ, Fillgrove KL, Lu B, Liang Y, Dubost DC, Puri V, Eddins DM, Vardigan JD, Drolet RE, Kern JT, Uslaner JM. Rudd MT, et al. Among authors: fillgrove kl. ACS Med Chem Lett. 2023 Jul 12;14(8):1088-1094. doi: 10.1021/acsmedchemlett.3c00210. eCollection 2023 Aug 10. ACS Med Chem Lett. 2023. PMID: 37583812
In Vitro Evaluation of the Drug Interaction Potential of Doravirine.
Bleasby K, Fillgrove KL, Houle R, Lu B, Palamanda J, Newton DJ, Lin M, Chan GH, Sanchez RI. Bleasby K, et al. Among authors: fillgrove kl. Antimicrob Agents Chemother. 2019 Mar 27;63(4):e02492-18. doi: 10.1128/AAC.02492-18. Print 2019 Apr. Antimicrob Agents Chemother. 2019. PMID: 30745395 Free PMC article.
Pyrazole Ureas as Low Dose, CNS Penetrant Glucosylceramide Synthase Inhibitors for the Treatment of Parkinson's Disease.
Roecker AJ, Schirripa KM, Loughran HM, Tong L, Liang T, Fillgrove KL, Kuo Y, Bleasby K, Collier H, Altman MD, Ford MC, Drolet RE, Cosden M, Jinn S, Hatcher NG, Yao L, Kandebo M, Vardigan JD, Flick RB, Liu X, Minnick C, Price LA, Watt ML, Lemaire W, Burlein C, Adam GC, Austin LA, Marcus JN, Smith SM, Fraley ME. Roecker AJ, et al. Among authors: fillgrove kl. ACS Med Chem Lett. 2023 Jan 12;14(2):146-155. doi: 10.1021/acsmedchemlett.2c00441. eCollection 2023 Feb 9. ACS Med Chem Lett. 2023. PMID: 36793422 Free PMC article.
Fluorinated Isoindolinone-Based Glucosylceramide Synthase Inhibitors with Low Human Dose Projections.
Loughran HM, Schirripa KM, Roecker AJ, Breslin MJ, Tong L, Fillgrove KL, Kuo Y, Bleasby K, Collier H, Altman MD, Ford MC, Newman JA, Drolet RE, Cosden M, Jinn S, Flick RB, Liu X, Minnick C, Watt ML, Lemaire W, Burlein C, Adam GC, Austin LA, Marcus JN, Smith SM, Fraley ME. Loughran HM, et al. Among authors: fillgrove kl. ACS Med Chem Lett. 2023 Dec 21;15(1):123-131. doi: 10.1021/acsmedchemlett.3c00436. eCollection 2024 Jan 11. ACS Med Chem Lett. 2023. PMID: 38229758
Lack of a Clinically Meaningful Drug Interaction Between the HIV-1 Antiretroviral Agents Islatravir, Dolutegravir, and Tenofovir Disoproxil Fumarate.
Rudd DJ, Zhang S, Fillgrove KL, Fox-Bosetti S, Matthews RP, Friedman E, Armas D, Stoch SA, Iwamoto M. Rudd DJ, et al. Among authors: fillgrove kl. Clin Pharmacol Drug Dev. 2021 Dec;10(12):1432-1441. doi: 10.1002/cpdd.1026. Epub 2021 Oct 22. Clin Pharmacol Drug Dev. 2021. PMID: 34676683 Free PMC article. Clinical Trial.
Extended-Duration MK-8591-Eluting Implant as a Candidate for HIV Treatment and Prevention.
Barrett SE, Teller RS, Forster SP, Li L, Mackey MA, Skomski D, Yang Z, Fillgrove KL, Doto GJ, Wood SL, Lebron J, Grobler JA, Sanchez RI, Liu Z, Lu B, Niu T, Sun L, Gindy ME. Barrett SE, et al. Among authors: fillgrove kl. Antimicrob Agents Chemother. 2018 Sep 24;62(10):e01058-18. doi: 10.1128/AAC.01058-18. Print 2018 Oct. Antimicrob Agents Chemother. 2018. PMID: 30012772 Free PMC article.
A phase 1, open-label study to evaluate the drug interaction between islatravir (MK-8591) and the oral contraceptive levonorgestrel/ethinyl estradiol in healthy adult females.
Ankrom W, Jackson Rudd D, Zhang S, Fillgrove KL, Gravesande KN, Matthews RP, Brimhall D, Stoch SA, Iwamoto MN. Ankrom W, et al. Among authors: fillgrove kl. J Int AIDS Soc. 2021 Dec;24(12):e25858. doi: 10.1002/jia2.25858. J Int AIDS Soc. 2021. PMID: 34935295 Free PMC article. Clinical Trial.
23 results