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Structural investigation of CDCA3-Cdh1 protein-protein interactions using in vitro studies and molecular dynamics simulation.
Barbhuiya TK, Fisher M, Boittier ED, Bolderson E, O'Byrne KJ, Richard DJ, Adams MN, Gandhi NS. Barbhuiya TK, et al. Protein Sci. 2023 Mar;32(3):e4572. doi: 10.1002/pro.4572. Protein Sci. 2023. PMID: 36691744 Free PMC article.
CDCA3 is an intrinsically disordered protein and contains both C-terminal KEN box and D-box recognition motifs, enabling binding to Cdh1. ...We identified the role of H-bonds, hydrophobic and ionic interactions across the CDCA3 ABBA-like motif in the linker region between …
CDCA3 is an intrinsically disordered protein and contains both C-terminal KEN box and D-box recognition motifs, enabling binding to C …