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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 11
2003 8
2004 7
2005 5
2006 9
2007 6
2008 10
2009 12
2010 9
2011 13
2012 22
2013 17
2014 15
2015 14
2016 14
2017 9
2018 15
2019 17
2020 21
2021 31
2022 10
2023 15
2024 5

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267 results

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Page 1
Semaglutide once a week in adults with overweight or obesity, with or without type 2 diabetes in an east Asian population (STEP 6): a randomised, double-blind, double-dummy, placebo-controlled, phase 3a trial.
Kadowaki T, Isendahl J, Khalid U, Lee SY, Nishida T, Ogawa W, Tobe K, Yamauchi T, Lim S; STEP 6 investigators. Kadowaki T, et al. Among authors: tobe k. Lancet Diabetes Endocrinol. 2022 Mar;10(3):193-206. doi: 10.1016/S2213-8587(22)00008-0. Epub 2022 Feb 4. Lancet Diabetes Endocrinol. 2022. PMID: 35131037 Clinical Trial.
Depletion of CD206+ M2-like macrophages induces fibro-adipogenic progenitors activation and muscle regeneration.
Nawaz A, Bilal M, Fujisaka S, Kado T, Aslam MR, Ahmed S, Okabe K, Igarashi Y, Watanabe Y, Kuwano T, Tsuneyama K, Nishimura A, Nishida Y, Yamamoto S, Sasahara M, Imura J, Mori H, Matzuk MM, Kudo F, Manabe I, Uezumi A, Nakagawa T, Oishi Y, Tobe K. Nawaz A, et al. Among authors: tobe k. Nat Commun. 2022 Nov 21;13(1):7058. doi: 10.1038/s41467-022-34191-y. Nat Commun. 2022. PMID: 36411280 Free PMC article.
Astaxanthin stimulates mitochondrial biogenesis in insulin resistant muscle via activation of AMPK pathway.
Nishida Y, Nawaz A, Kado T, Takikawa A, Igarashi Y, Onogi Y, Wada T, Sasaoka T, Yamamoto S, Sasahara M, Imura J, Tokuyama K, Usui I, Nakagawa T, Fujisaka S, Kunimasa Y, Tobe K. Nishida Y, et al. Among authors: tobe k. J Cachexia Sarcopenia Muscle. 2020 Feb;11(1):241-258. doi: 10.1002/jcsm.12530. Epub 2020 Jan 31. J Cachexia Sarcopenia Muscle. 2020. PMID: 32003547 Free PMC article.
The gut microbiome: a core regulator of metabolism.
Fujisaka S, Watanabe Y, Tobe K. Fujisaka S, et al. Among authors: tobe k. J Endocrinol. 2023 Jan 19;256(3):e220111. doi: 10.1530/JOE-22-0111. Print 2023 Mar 1. J Endocrinol. 2023. PMID: 36458804 Free PMC article. Review.
Hepatic FASN deficiency differentially affects nonalcoholic fatty liver disease and diabetes in mouse obesity models.
Matsukawa T, Yagi T, Uchida T, Sakai M, Mitsushima M, Naganuma T, Yano H, Inaba Y, Inoue H, Yanagida K, Uematsu M, Nakao K, Nakao H, Aiba A, Nagashima Y, Kubota T, Kubota N, Izumida Y, Yahagi N, Unoki-Kubota H, Kaburagi Y, Asahara SI, Kido Y, Shindou H, Itoh M, Ogawa Y, Minami S, Terauchi Y, Tobe K, Ueki K, Kasuga M, Matsumoto M. Matsukawa T, et al. Among authors: tobe k. JCI Insight. 2023 Sep 8;8(17):e161282. doi: 10.1172/jci.insight.161282. JCI Insight. 2023. PMID: 37681411 Free PMC article.
Effect of an intensified multifactorial intervention on cardiovascular outcomes and mortality in type 2 diabetes (J-DOIT3): an open-label, randomised controlled trial.
Ueki K, Sasako T, Okazaki Y, Kato M, Okahata S, Katsuyama H, Haraguchi M, Morita A, Ohashi K, Hara K, Morise A, Izumi K, Ishizuka N, Ohashi Y, Noda M, Kadowaki T; J-DOIT3 Study Group. Ueki K, et al. Lancet Diabetes Endocrinol. 2017 Dec;5(12):951-964. doi: 10.1016/S2213-8587(17)30327-3. Epub 2017 Oct 24. Lancet Diabetes Endocrinol. 2017. PMID: 29079252 Clinical Trial.
Isoxanthohumol improves obesity and glucose metabolism via inhibiting intestinal lipid absorption with a bloom of Akkermansia muciniphila in mice.
Watanabe Y, Fujisaka S, Morinaga Y, Watanabe S, Nawaz A, Hatta H, Kado T, Nishimura A, Bilal M, Aslam MR, Honda K, Nakagawa Y, Softic S, Hirabayashi K, Nakagawa T, Nagai Y, Tobe K. Watanabe Y, et al. Among authors: tobe k. Mol Metab. 2023 Nov;77:101797. doi: 10.1016/j.molmet.2023.101797. Epub 2023 Sep 12. Mol Metab. 2023. PMID: 37709134 Free PMC article.
267 results