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Syntheses of 25-Adamantyl-25-alkyl-2-methylidene-1α,25-dihydroxyvitamin D3 Derivatives with Structure-Function Studies of Antagonistic and Agonistic Active Vitamin D Analogs.
Biomolecules. 2023 Jul 6;13(7):1082. doi: 10.3390/biom13071082.
Biomolecules. 2023.
PMID: 37509118
Free PMC article.
Combination of triple bond and adamantane ring on the vitamin D side chain produced partial agonists for vitamin D receptor.
Kudo T, Ishizawa M, Maekawa K, Nakabayashi M, Watarai Y, Uchida H, Tokiwa H, Ikura T, Ito N, Makishima M, Yamada S.
Kudo T, et al. Among authors: maekawa k.
J Med Chem. 2014 May 22;57(10):4073-87. doi: 10.1021/jm401989c. Epub 2014 May 7.
J Med Chem. 2014.
PMID: 24773565
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