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Discovery of the Orally Effective Thyrotropin-Releasing Hormone Mimetic: 1-{N-[(4S,5S)-(5-Methyl-2-oxooxazolidine-4-yl)carbonyl]-3-(thiazol-4-yl)-l-alanyl}-(2R)-2-methylpyrrolidine Trihydrate (Rovatirelin Hydrate).
Kobayashi N, Sato N, Fujimura Y, Kihara T, Sugita K, Takahashi K, Koike K, Sugawara T, Tada Y, Nakai H, Yoshikawa T. Kobayashi N, et al. Among authors: sugita k. ACS Omega. 2018 Oct 31;3(10):13647-13666. doi: 10.1021/acsomega.8b01481. Epub 2018 Oct 19. ACS Omega. 2018. PMID: 30411045 Free PMC article.
Synthesis and Evaluation of in Vivo Anti-hypothermic Effect of the N- and C-Terminus Modified Thyrotropin-Releasing Hormone Mimetic: [(4S,5S)-(5-Methyl-2-oxooxazolidine-4-yl)carbonyl]-[3-(thiazol-4-yl)-L-alanyl]-L-prolinamide.
Kobayashi N, Sato N, Sugita K, Kihara T, Koike K, Sugawara T, Tada Y, Yoshikawa T. Kobayashi N, et al. Among authors: sugita k. Chem Pharm Bull (Tokyo). 2021;69(4):314-324. doi: 10.1248/cpb.c20-00454. Chem Pharm Bull (Tokyo). 2021. PMID: 33790077 Free article.
Correction to Discovery of the Orally Effective Thyrotropin-Releasing Hormone Mimetic: 1-{N-[(4S,5S)-(5-Methyl-2-oxooxazolidine-4-yl)carbonyl]-3-(thiazol-4-yl)-l-alanyl}-(2R)-2-methylpyrrolidine Trihydrate (Rovatirelin Hydrate).
Kobayashi N, Sato N, Fujimura Y, Kihara T, Sugita K, Takahashi K, Koike K, Sugawara T, Tada Y, Nakai H, Yoshikawa T. Kobayashi N, et al. Among authors: sugita k. ACS Omega. 2019 Apr 17;4(4):6977-6978. doi: 10.1021/acsomega.9b00827. eCollection 2019 Apr 30. ACS Omega. 2019. PMID: 31459810 Free PMC article.