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Page 1
Discovery of the Orally Effective Thyrotropin-Releasing Hormone Mimetic: 1-{N-[(4S,5S)-(5-Methyl-2-oxooxazolidine-4-yl)carbonyl]-3-(thiazol-4-yl)-l-alanyl}-(2R)-2-methylpyrrolidine Trihydrate (Rovatirelin Hydrate).
ACS Omega. 2018 Oct 31;3(10):13647-13666. doi: 10.1021/acsomega.8b01481. Epub 2018 Oct 19.
ACS Omega. 2018.
PMID: 30411045
Free PMC article.
Formation of Hemihydrate Crystal form Overcomes Milling Issue Induced by Exposed Functional Groups on Cleavage Plane for a Y5 Receptor Antagonist of Neuropeptide Y.
Nagamatsu D, Ando S, Fujimura Y, Miyano T, Sugita K, Ueda H.
Nagamatsu D, et al. Among authors: sugita k.
J Pharm Sci. 2023 Sep;112(9):2516-2523. doi: 10.1016/j.xphs.2023.04.012. Epub 2023 Apr 24.
J Pharm Sci. 2023.
PMID: 37100203
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Synthesis and Evaluation of in Vivo Anti-hypothermic Effect of the N- and C-Terminus Modified Thyrotropin-Releasing Hormone Mimetic: [(4S,5S)-(5-Methyl-2-oxooxazolidine-4-yl)carbonyl]-[3-(thiazol-4-yl)-L-alanyl]-L-prolinamide.
Kobayashi N, Sato N, Sugita K, Kihara T, Koike K, Sugawara T, Tada Y, Yoshikawa T.
Kobayashi N, et al. Among authors: sugita k.
Chem Pharm Bull (Tokyo). 2021;69(4):314-324. doi: 10.1248/cpb.c20-00454.
Chem Pharm Bull (Tokyo). 2021.
PMID: 33790077
Free article.
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Applicability of an Experimental Grade of Hydroxypropyl Methylcellulose Acetate Succinate as a Carrier for Formation of Solid Dispersion with Indomethacin.
Ueda H, Hirakawa Y, Tanaka H, Miyano T, Sugita K.
Ueda H, et al. Among authors: sugita k.
Pharmaceutics. 2021 Mar 8;13(3):353. doi: 10.3390/pharmaceutics13030353.
Pharmaceutics. 2021.
PMID: 33800229
Free PMC article.
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Correction to Discovery of the Orally Effective Thyrotropin-Releasing Hormone Mimetic: 1-{N-[(4S,5S)-(5-Methyl-2-oxooxazolidine-4-yl)carbonyl]-3-(thiazol-4-yl)-l-alanyl}-(2R)-2-methylpyrrolidine Trihydrate (Rovatirelin Hydrate).
Kobayashi N, Sato N, Fujimura Y, Kihara T, Sugita K, Takahashi K, Koike K, Sugawara T, Tada Y, Nakai H, Yoshikawa T.
Kobayashi N, et al. Among authors: sugita k.
ACS Omega. 2019 Apr 17;4(4):6977-6978. doi: 10.1021/acsomega.9b00827. eCollection 2019 Apr 30.
ACS Omega. 2019.
PMID: 31459810
Free PMC article.
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Synthesis and evaluation of in vivo anti-hypothermic effect of all stereoisomers of the thyrotropin-releasing hormone mimetic: Rovatirelin Hydrate.
Kobayashi N, Sato N, Sugita K, Takahashi K, Sugawara T, Tada Y, Yoshikawa T.
Kobayashi N, et al. Among authors: sugita k.
J Pept Sci. 2019 Dec;25(12):e3228. doi: 10.1002/psc.3228. Epub 2019 Nov 12.
J Pept Sci. 2019.
PMID: 31713944
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