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Tumor suppressor NF2/Merlin is a microtubule stabilizer.
Smole Z, Thoma CR, Applegate KT, Duda M, Gutbrodt KL, Danuser G, Krek W. Smole Z, et al. Among authors: gutbrodt kl. Cancer Res. 2014 Jan 1;74(1):353-62. doi: 10.1158/0008-5472.CAN-13-1334. Epub 2013 Nov 26. Cancer Res. 2014. PMID: 24282279 Free PMC article.
VHL loss causes spindle misorientation and chromosome instability.
Thoma CR, Toso A, Gutbrodt KL, Reggi SP, Frew IJ, Schraml P, Hergovich A, Moch H, Meraldi P, Krek W. Thoma CR, et al. Among authors: gutbrodt kl. Nat Cell Biol. 2009 Aug;11(8):994-1001. doi: 10.1038/ncb1912. Epub 2009 Jul 20. Nat Cell Biol. 2009. PMID: 19620968
Targeting interleukin-2 to the bone marrow stroma for therapy of acute myeloid leukemia relapsing after allogeneic hematopoietic stem cell transplantation.
Schliemann C, Gutbrodt KL, Kerkhoff A, Pohlen M, Wiebe S, Silling G, Angenendt L, Kessler T, Mesters RM, Giovannoni L, Schäfers M, Altvater B, Rossig C, Grünewald I, Wardelmann E, Köhler G, Neri D, Stelljes M, Berdel WE. Schliemann C, et al. Among authors: gutbrodt kl. Cancer Immunol Res. 2015 May;3(5):547-56. doi: 10.1158/2326-6066.CIR-14-0179. Epub 2015 Feb 11. Cancer Immunol Res. 2015. PMID: 25672398