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Page 1
Structure, Roles and Inhibitors of a Mitotic Protein Kinase Haspin.
Curr Med Chem. 2017;24(21):2276-2293. doi: 10.2174/0929867324666170414155520.
Curr Med Chem. 2017.
PMID: 28413956
Review.
Bisubstrate inhibitor approach for targeting mitotic kinase Haspin.
Kestav K, Lavogina D, Raidaru G, Chaikuad A, Knapp S, Uri A.
Kestav K, et al.
Bioconjug Chem. 2015 Feb 18;26(2):225-34. doi: 10.1021/bc500464r. Epub 2015 Jan 29.
Bioconjug Chem. 2015.
PMID: 25595038
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Co-crystal structures of the protein kinase haspin with bisubstrate inhibitors.
Lavogina D, Kestav K, Chaikuad A, Heroven C, Knapp S, Uri A.
Lavogina D, et al. Among authors: kestav k.
Acta Crystallogr F Struct Biol Commun. 2016 May;72(Pt 5):339-45. doi: 10.1107/S2053230X16004611. Epub 2016 Apr 22.
Acta Crystallogr F Struct Biol Commun. 2016.
PMID: 27139824
Free PMC article.
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Crystal Structure-Guided Design of Bisubstrate Inhibitors and Photoluminescent Probes for Protein Kinases of the PIM Family.
Nonga OE, Lavogina D, Enkvist E, Kestav K, Chaikuad A, Dixon-Clarke SE, Bullock AN, Kopanchuk S, Ivan T, Ekambaram R, Viht K, Knapp S, Uri A.
Nonga OE, et al. Among authors: kestav k.
Molecules. 2021 Jul 19;26(14):4353. doi: 10.3390/molecules26144353.
Molecules. 2021.
PMID: 34299628
Free PMC article.
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Slowly on, Slowly off: Bisubstrate-Analogue Conjugates of 5-Iodotubercidin and Histone H3 Peptide Targeting Protein Kinase Haspin.
Kestav K, Viht K, Konovalov A, Enkvist E, Uri A, Lavogina D.
Kestav K, et al.
Chembiochem. 2017 Apr 18;18(8):790-798. doi: 10.1002/cbic.201600697. Epub 2017 Mar 21.
Chembiochem. 2017.
PMID: 28181383
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