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Untargeted proteomics reveals upregulation of stress response pathways during CHO-based monoclonal antibody manufacturing process leading to disulfide bond reduction.
MAbs. 2021 Jan-Dec;13(1):1963094. doi: 10.1080/19420862.2021.1963094.
MAbs. 2021.
PMID: 34424810
Free PMC article.
Metabolomic and quality data for early and late passages of an antibody-producing industrial CHO cell line.
Sowa SW, Qian Y, Aron KL, Xu P, Langsdorf E, Warrack B, Aranibar N, Tremml G, Xu J, McVey D, Reily M, Khetan A, Borys MC, Li ZJ.
Sowa SW, et al. Among authors: aron kl.
Data Brief. 2020 Nov 26;33:106591. doi: 10.1016/j.dib.2020.106591. eCollection 2020 Dec.
Data Brief. 2020.
PMID: 33318978
Free PMC article.
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Effective temperature shift strategy development and scale confirmation for simultaneous optimization of protein productivity and quality in Chinese hamster ovary cells.
McHugh KP, Xu J, Aron KL, Borys MC, Li ZJ.
McHugh KP, et al. Among authors: aron kl.
Biotechnol Prog. 2020 May;36(3):e2959. doi: 10.1002/btpr.2959. Epub 2020 Jan 17.
Biotechnol Prog. 2020.
PMID: 31930722
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