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Page 1
The Pediatric Precision Oncology INFORM Registry: Clinical Outcome and Benefit for Patients with Very High-Evidence Targets.
van Tilburg CM, Pfaff E, Pajtler KW, Langenberg KPS, Fiesel P, Jones BC, Balasubramanian GP, Stark S, Johann PD, Blattner-Johnson M, Schramm K, Dikow N, Hirsch S, Sutter C, Grund K, von Stackelberg A, Kulozik AE, Lissat A, Borkhardt A, Meisel R, Reinhardt D, Klusmann JH, Fleischhack G, Tippelt S, von Schweinitz D, Schmid I, Kramm CM, von Bueren AO, Calaminus G, Vorwerk P, Graf N, Westermann F, Fischer M, Eggert A, Burkhardt B, Wößmann W, Nathrath M, Hecker-Nolting S, Frühwald MC, Schneider DT, Brecht IB, Ketteler P, Fulda S, Koscielniak E, Meister MT, Scheer M, Hettmer S, Schwab M, Tremmel R, Øra I, Hutter C, Gerber NU, Lohi O, Kazanowska B, Kattamis A, Filippidou M, Goemans B, Zwaan CM, Milde T, Jäger N, Wolf S, Reuss D, Sahm F, von Deimling A, Dirksen U, Freitag A, Witt R, Lichter P, Kopp-Schneider A, Jones DTW, Molenaar JJ, Capper D, Pfister SM, Witt O. van Tilburg CM, et al. Among authors: schramm k. Cancer Discov. 2021 Nov;11(11):2764-2779. doi: 10.1158/2159-8290.CD-21-0094. Epub 2021 Aug 9. Cancer Discov. 2021. PMID: 34373263 Free PMC article.
Amplification of the PLAG-family genes-PLAGL1 and PLAGL2-is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification.
Keck MK, Sill M, Wittmann A, Joshi P, Stichel D, Beck P, Okonechnikow K, Sievers P, Wefers AK, Roncaroli F, Avula S, McCabe MG, Hayden JT, Wesseling P, Øra I, Nistér M, Kranendonk MEG, Tops BBJ, Zapotocky M, Zamecnik J, Vasiljevic A, Fenouil T, Meyronet D, von Hoff K, Schüller U, Loiseau H, Figarella-Branger D, Kramm CM, Sturm D, Scheie D, Rauramaa T, Pesola J, Gojo J, Haberler C, Brandner S, Jacques T, Sexton Oates A, Saffery R, Koscielniak E, Baker SJ, Yip S, Snuderl M, Ud Din N, Samuel D, Schramm K, Blattner-Johnson M, Selt F, Ecker J, Milde T, von Deimling A, Korshunov A, Perry A, Pfister SM, Sahm F, Solomon DA, Jones DTW. Keck MK, et al. Among authors: schramm k. Acta Neuropathol. 2023 Jan;145(1):49-69. doi: 10.1007/s00401-022-02516-2. Epub 2022 Nov 27. Acta Neuropathol. 2023. PMID: 36437415 Free PMC article.
Drug sensitivity profiling of 3D tumor tissue cultures in the pediatric precision oncology program INFORM.
Peterziel H, Jamaladdin N, ElHarouni D, Gerloff XF, Herter S, Fiesel P, Berker Y, Blattner-Johnson M, Schramm K, Jones BC, Reuss D, Turunen L, Friedenauer A, Holland-Letz T, Sill M, Weiser L, Previti C, Balasubramanian G, Gerber NU, Gojo J, Hutter C, Øra I, Lohi O, Kattamis A, de Wilde B, Westermann F, Tippelt S, Graf N, Nathrath M, Sparber-Sauer M, Sehested A, Kramm CM, Dirksen U, Kallioniemi O, Pfister SM, van Tilburg CM, Jones DTW, Saarela J, Pietiäinen V, Jäger N, Schlesner M, Kopp-Schneider A, Oppermann S, Milde T, Witt O, Oehme I. Peterziel H, et al. Among authors: schramm k. NPJ Precis Oncol. 2022 Dec 27;6(1):94. doi: 10.1038/s41698-022-00335-y. NPJ Precis Oncol. 2022. PMID: 36575299 Free PMC article.
Genomic ALK alterations in primary and relapsed neuroblastoma.
Rosswog C, Fassunke J, Ernst A, Schömig-Markiefka B, Merkelbach-Bruse S, Bartenhagen C, Cartolano M, Ackermann S, Theissen J, Blattner-Johnson M, Jones B, Schramm K, Altmüller J, Nürnberg P, Ortmann M, Berthold F, Peifer M, Büttner R, Westermann F, Schulte JH, Simon T, Hero B, Fischer M. Rosswog C, et al. Among authors: schramm k. Br J Cancer. 2023 Apr;128(8):1559-1571. doi: 10.1038/s41416-023-02208-y. Epub 2023 Feb 17. Br J Cancer. 2023. PMID: 36807339 Free PMC article.
Outcome of Children and Adolescents With Relapsed/Refractory/Progressive Malignancies Treated With Molecularly Informed Targeted Drugs in the Pediatric Precision Oncology Registry INFORM.
Heipertz AE, Pajtler KW, Pfaff E, Schramm K, Blattner-Johnson M, Milde T, Jones BC, Zuliani C, Hutter C, Lohi O, Kattamis A, Dachowska-Kalwak I, Nilsson A, Gerber NU, Langenberg KPS, Goemans B, Zwaan CM, Molenaar JJ, Jäger N, Dirksen U, Witt R, Pfister SM, Jones DTW, Kopp-Schneider A, Witt O, van Tilburg CM. Heipertz AE, et al. Among authors: schramm k. JCO Precis Oncol. 2023 Jun;7:e2300015. doi: 10.1200/PO.23.00015. JCO Precis Oncol. 2023. PMID: 37364231
Secondary Biphenotypic Acute Leukemia Following Rosai-Dorfman-Disease A Coincidence?
Thieme A, Maurus K, Ernestus K, Hirsch S, Schramm K, Wirth C, Buck A, Härtel C, Schlegel PG, Eyrich M, Woelfl M, Classen CF, Wiegering VA. Thieme A, et al. Among authors: schramm k. Klin Padiatr. 2022 May;234(3):169-171. doi: 10.1055/a-1699-3016. Epub 2021 Dec 15. Klin Padiatr. 2022. PMID: 34911134 Free PMC article. No abstract available.
Functional Therapeutic Target Validation Using Pediatric Zebrafish Xenograft Models.
Gatzweiler C, Ridinger J, Herter S, Gerloff XF, ElHarouni D, Berker Y, Imle R, Schmitt L, Kreth S, Stainczyk S, Ayhan S, Najafi S, Krunic D, Frese K, Meder B, Reuss D, Fiesel P, Schramm K, Blattner-Johnson M, Jones DTW, Banito A, Westermann F, Oppermann S, Milde T, Peterziel H, Witt O, Oehme I. Gatzweiler C, et al. Among authors: schramm k. Cancers (Basel). 2022 Feb 8;14(3):849. doi: 10.3390/cancers14030849. Cancers (Basel). 2022. PMID: 35159116 Free PMC article.
Genomic Evolution and Personalized Therapy of an Infantile Fibrosarcoma Harboring an NTRK Oncogenic Fusion.
Thorwarth A, Haase K, Röefzaad C, Pajtler KW, Schramm K, Hauptmann K, Behnke A, Vokuhl C, Elgeti T, Gratopp A, Schulte JH, Scheer M, Hernáiz Driever P, Nysom K, Eggert A, Henssen AG, Deubzer HE. Thorwarth A, et al. Among authors: schramm k. JCO Precis Oncol. 2022 May;6:e2100283. doi: 10.1200/PO.21.00283. JCO Precis Oncol. 2022. PMID: 35613412 Free PMC article. No abstract available.
Nuclear Calcium Buffering Capacity Shapes Neuronal Architecture.
Mauceri D, Hagenston AM, Schramm K, Weiss U, Bading H. Mauceri D, et al. Among authors: schramm k. J Biol Chem. 2015 Sep 18;290(38):23039-49. doi: 10.1074/jbc.M115.654962. Epub 2015 Jul 31. J Biol Chem. 2015. PMID: 26231212 Free PMC article.
16 results