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Neuropathic and cAMP-induced pain behavior is ameliorated in mice lacking CNGB1.
Kallenborn-Gerhardt W, Metzner K, Lu R, Petersen J, Kuth MS, Heine S, Drees O, Paul M, Becirovic E, Kennel L, Flauaus C, Gross T, Wack G, Hohmann SW, Nemirovski D, Del Turco D, Biel M, Geisslinger G, Michalakis S, Schmidtko A. Kallenborn-Gerhardt W, et al. Among authors: metzner k. Neuropharmacology. 2020 Jul;171:108087. doi: 10.1016/j.neuropharm.2020.108087. Epub 2020 Apr 6. Neuropharmacology. 2020. PMID: 32272140
DPP10 is a new regulator of Nav1.5 channels in human heart.
Belau F, Metzner K, Christ T, Ravens U, Schaefer M, Künzel S, Li W, Wettwer E, Dobrev D, El-Armouche A, Kämmerer S. Belau F, et al. Among authors: metzner k. Int J Cardiol. 2019 Jun 1;284:68-73. doi: 10.1016/j.ijcard.2018.12.072. Epub 2019 Jan 3. Int J Cardiol. 2019. PMID: 30638748
Discovery of a Small Molecule Activator of Slack (Kcnt1) Potassium Channels That Significantly Reduces Scratching in Mouse Models of Histamine-Independent and Chronic Itch.
Balzulat A, Zhu WF, Flauaus C, Hernandez-Olmos V, Heering J, Sethumadhavan S, Dubiel M, Frank A, Menge A, Hebchen M, Metzner K, Lu R, Lukowski R, Ruth P, Knapp S, Müller S, Steinhilber D, Hänelt I, Stark H, Proschak E, Schmidtko A. Balzulat A, et al. Among authors: metzner k. Adv Sci (Weinh). 2024 Apr;11(15):e2307237. doi: 10.1002/advs.202307237. Epub 2024 Feb 13. Adv Sci (Weinh). 2024. PMID: 38350720 Free PMC article.