Carbon nanofiber-based glucose biosensor

Vicky Vamvakaki; Katerina Tsagaraki; Nikos Chaniotakis

doi:10.1021/ac060551t

Carbon nanofiber-based glucose biosensor

Anal Chem. 2006 Aug 1;78(15):5538-42. doi: 10.1021/ac060551t.

Authors

Vicky Vamvakaki¹, Katerina Tsagaraki, Nikos Chaniotakis

Affiliation

¹ Laboratory of Analytical Chemistry, Department of Chemistry, University of Crete, P.O. Box 2208, 71003 Voutes Iraklion, Crete, Greece.

PMID: 16878893
DOI: 10.1021/ac060551t

Abstract

The use of highly activated carbon nanofibers for the design of catalytic electrochemical biosensors is demonstrated. The direct immobilization of enzymes onto the surface of carbon nanofibers is shown to be a highly efficient method for the development of a new class of very sensitive, stable, and reproducible electrochemical biosensors. These results establish the fact that the carbon nanofiber is the best matrix so far described for the development of biosensors, far superior to carbon nanotubes or graphite powder.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Biosensing Techniques / methods*
Electrochemistry
Enzymes, Immobilized / chemistry*
Glucose / analysis*
Glucose Oxidase / chemistry*
Graphite / chemistry*
Hydrogen-Ion Concentration
Nanotubes, Carbon / chemistry*
Particle Size
Reproducibility of Results
Sensitivity and Specificity
Surface Properties

Substances

Enzymes, Immobilized
Nanotubes, Carbon
Graphite
Glucose Oxidase
Glucose