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Page 1
Current Trends in Sirtuin Activator and Inhibitor Development.
Molecules. 2024 Mar 6;29(5):1185. doi: 10.3390/molecules29051185.
Molecules. 2024.
PMID: 38474697
Free PMC article.
Review.
Analysis of continuous enzyme kinetic data using ICEKAT.
Bursch KL, Olp MD, Smith BC.
Bursch KL, et al.
Methods Enzymol. 2023;690:109-129. doi: 10.1016/bs.mie.2023.06.019. Epub 2023 Jul 29.
Methods Enzymol. 2023.
PMID: 37858527
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Selective and Cell-Active PBRM1 Bromodomain Inhibitors Discovered through NMR Fragment Screening.
Shishodia S, Nuñez R, Strohmier BP, Bursch KL, Goetz CJ, Olp MD, Jensen DR, Fenske TG, Ordonez-Rubiano SC, Blau ME, Roach MK, Peterson FC, Volkman BF, Dykhuizen EC, Smith BC.
Shishodia S, et al. Among authors: bursch kl.
J Med Chem. 2022 Oct 27;65(20):13714-13735. doi: 10.1021/acs.jmedchem.2c00864. Epub 2022 Oct 13.
J Med Chem. 2022.
PMID: 36227159
Free PMC article.
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Cancer-associated polybromo-1 bromodomain 4 missense variants variably impact bromodomain ligand binding and cell growth suppression.
Bursch KL, Goetz CJ, Jiao G, Nuñez R, Olp MD, Dhiman A, Khurana M, Zimmermann MT, Urrutia RA, Dykhuizen EC, Smith BC.
Bursch KL, et al.
J Biol Chem. 2024 Apr;300(4):107146. doi: 10.1016/j.jbc.2024.107146. Epub 2024 Mar 7.
J Biol Chem. 2024.
PMID: 38460939
Free PMC article.
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