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Selective modifications of lactose and N-acetyllactosamine with sulfate and aromatic bulky groups unveil unique structural insights in galectin-1-ligand recognition.
Bioorg Med Chem. 2023 Oct 30;94:117480. doi: 10.1016/j.bmc.2023.117480. Epub 2023 Sep 21.
Bioorg Med Chem. 2023.
PMID: 37774448
Free article.
Teaming up synthetic chemistry and histochemistry for activity screening in galectin-directed inhibitor design.
Roy R, Cao Y, Kaltner H, Kottari N, Shiao TC, Belkhadem K, André S, Manning JC, Murphy PV, Gabius HJ.
Roy R, et al. Among authors: belkhadem k.
Histochem Cell Biol. 2017 Feb;147(2):285-301. doi: 10.1007/s00418-016-1525-5. Epub 2016 Dec 24.
Histochem Cell Biol. 2017.
PMID: 28013366
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Synthesis of 3-Alkyl Oxazolidines, Derived from 2-Hydroxymethyl Piperidine, as Analytical Standards for the Analysis of Volatile Aldehydes in the Workplace.
R Yaya A, Girard M, Belkhadem K, Piard R, Decken A, Choinière C, Cloutier PL, Lesage J, Breau L.
R Yaya A, et al. Among authors: belkhadem k.
ACS Omega. 2023 Jul 17;8(30):26793-26805. doi: 10.1021/acsomega.3c00961. eCollection 2023 Aug 1.
ACS Omega. 2023.
PMID: 37546669
Free PMC article.
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Synthesis of Galectin Inhibitors by Regioselective 3'-O-Sulfation of Vanillin Lactosides Obtained under Phase Transfer Catalysis.
Belkhadem K, Cao Y, Roy R.
Belkhadem K, et al.
Molecules. 2020 Dec 29;26(1):115. doi: 10.3390/molecules26010115.
Molecules. 2020.
PMID: 33383774
Free PMC article.
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