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Topoisomerase 1 inhibits MYC promoter activity by inducing G-quadruplex formation.
Keller JG, Hymøller KM, Thorsager ME, Hansen NY, Erlandsen JU, Tesauro C, Simonsen AKW, Andersen AB, Vandsø Petersen K, Holm LL, Stougaard M, Andresen BS, Kristensen P, Frøhlich R, Knudsen BR. Keller JG, et al. Among authors: vandso petersen k. Nucleic Acids Res. 2022 Jun 24;50(11):6332-6342. doi: 10.1093/nar/gkac482. Nucleic Acids Res. 2022. PMID: 35687110 Free PMC article.
Gel-Free Tools for Quick and Simple Screening of Anti-Topoisomerase 1 Compounds.
Keller JG, Petersen KV, Mizielinski K, Thiesen C, Bjergbæk L, Reguera RM, Pérez-Pertejo Y, Balaña-Fouce R, Trejo A, Masdeu C, Alonso C, Knudsen BR, Tesauro C. Keller JG, et al. Among authors: petersen kv. Pharmaceuticals (Basel). 2023 Apr 27;16(5):657. doi: 10.3390/ph16050657. Pharmaceuticals (Basel). 2023. PMID: 37242440 Free PMC article.