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REST Inactivation and Coexpression of ASCL1 and POU3F4 Are Necessary for the Complete Transformation of RB1/TP53-Inactivated Lung Adenocarcinoma into Neuroendocrine Carcinoma.
Masawa M, Sato-Yazawa H, Kashiwagi K, Ishii J, Miyata-Hiramatsu C, Iwamoto M, Kohno K, Miyazawa T, Onozaki M, Noda S, Shimizu Y, Niho S, Yazawa T. Masawa M, et al. Among authors: kohno k. Am J Pathol. 2022 Jun;192(6):847-861. doi: 10.1016/j.ajpath.2022.03.007. Epub 2022 Mar 30. Am J Pathol. 2022. PMID: 35367201 Free article.
Endocrine secretory granule production is caused by a lack of REST and intragranular secretory content and accelerated by PROX1.
Ishii J, Sato-Yazawa H, Kashiwagi K, Nakadate K, Iwamoto M, Kohno K, Miyata-Hiramatsu C, Masawa M, Onozaki M, Noda S, Miyazawa T, Takagi M, Yazawa T. Ishii J, et al. Among authors: kohno k. J Mol Histol. 2022 Apr;53(2):437-448. doi: 10.1007/s10735-021-10055-5. Epub 2022 Jan 30. J Mol Histol. 2022. PMID: 35094211 Free PMC article.