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Automatic transcription factor classifier based on functional domain composition.
Qian Z, Cai YD, Li Y. Qian Z, et al. Biochem Biophys Res Commun. 2006 Aug 18;347(1):141-4. doi: 10.1016/j.bbrc.2006.06.060. Epub 2006 Jun 21. Biochem Biophys Res Commun. 2006. PMID: 16808896
We trained and tested our method on a non-redundancy dataset consisting of 74 transcription factors collected from TRANSFAC v7.0 [V. Matys, O.V. Kel-Margoulis, E. Fricke, I. Liebich, S. Land, A. Barre-Dirrie, I. Reuter, D. Chekmenev, M. Krull, K. Hornischer, …
We trained and tested our method on a non-redundancy dataset consisting of 74 transcription factors collected from TRANSFAC v7.0 [V. …
Presentation, care, and outcomes of patients with NSTEMI according to World Bank country income classification: the ACVC-EAPCI EORP NSTEMI Registry of the European Society of Cardiology.
Nadarajah R, Ludman P, Laroche C, Appelman Y, Brugaletta S, Budaj A, Bueno H, Huber K, Kunadian V, Leonardi S, Lettino M, Milasinovic D, Gale CP; NSTEMI investigator group. Nadarajah R, et al. Eur Heart J Qual Care Clin Outcomes. 2023 Sep 12;9(6):552-563. doi: 10.1093/ehjqcco/qcad008. Eur Heart J Qual Care Clin Outcomes. 2023. PMID: 36737420 Free PMC article.
Synthesis, biological evaluation, and molecular modeling of 11H-indeno[1,2-b]quinoxalin-11-one derivatives and tryptanthrin-6-oxime as c-Jun N-terminal kinase inhibitors.
Schepetkin IA, Khlebnikov AI, Potapov AS, Kovrizhina AR, Matveevskaya VV, Belyanin ML, Atochin DN, Zanoza SO, Gaidarzhy NM, Lyakhov SA, Kirpotina LN, Quinn MT. Schepetkin IA, et al. Eur J Med Chem. 2019 Jan 1;161:179-191. doi: 10.1016/j.ejmech.2018.10.023. Epub 2018 Oct 12. Eur J Med Chem. 2019. PMID: 30347329 Free PMC article.
The most potent compounds were 10c (11H-indeno[1,2-b]quinoxalin-11-one O-(O-ethylcarboxymethyl) oxime) and tryptanthrin-6-oxime, which had dissociation constants (K(d)) for JNK1 and JNK3 of 22 and 76 nM and 150 and 275 nM, respectively. ...
The most potent compounds were 10c (11H-indeno[1,2-b]quinoxalin-11-one O-(O-ethylcarboxymethyl) oxime) and tryptanthrin-6-oxime, which had d …
Vaginal progesterone reduces the rate of preterm birth in women with a sonographic short cervix: a multicenter, randomized, double-blind, placebo-controlled trial.
Hassan SS, Romero R, Vidyadhari D, Fusey S, Baxter JK, Khandelwal M, Vijayaraghavan J, Trivedi Y, Soma-Pillay P, Sambarey P, Dayal A, Potapov V, O'Brien J, Astakhov V, Yuzko O, Kinzler W, Dattel B, Sehdev H, Mazheika L, Manchulenko D, Gervasi MT, Sullivan L, Conde-Agudelo A, Phillips JA, Creasy GW; PREGNANT Trial. Hassan SS, et al. Ultrasound Obstet Gynecol. 2011 Jul;38(1):18-31. doi: 10.1002/uog.9017. Epub 2011 Jun 15. Ultrasound Obstet Gynecol. 2011. PMID: 21472815 Free PMC article. Clinical Trial.
[Comparative analysis of mono- and bipolar pyramidal tract mapping in patients with supratentorial tumors adjacent to motor areas: comparison of data at 64 stimulation points].
Kosyrkova AV, Goryainov SA, Ogurtsova AA, Okhlopkov VA, Kravchuk AD, Batalov AI, Afandiev RM, Bayev AA, Pogosbekyan EL, Pronin IN, Zakharova NE, Danilov GV, Strunina YV, Potapov AA. Kosyrkova AV, et al. Zh Vopr Neirokhir Im N N Burdenko. 2020;84(5):29-40. doi: 10.17116/neiro20208405129. Zh Vopr Neirokhir Im N N Burdenko. 2020. PMID: 33095531 Clinical Trial. Russian.
Identity of the exchangeable sulfur-containing ligand at the Mo(V) center of R160Q human sulfite oxidase.
Klein EL, Raitsimring AM, Astashkin AV, Rajapakshe A, Johnson-Winters K, Arnold AR, Potapov A, Goldfarb D, Enemark JH. Klein EL, et al. Inorg Chem. 2012 Feb 6;51(3):1408-18. doi: 10.1021/ic201643t. Epub 2012 Jan 6. Inorg Chem. 2012. PMID: 22225516 Free PMC article.
In our previous study of the fatal R160Q mutant of human sulfite oxidase (hSO) at low pH (Astashkin et al. J. Am. Chem. Soc.2008, 130, 8471-8480), a new Mo(V) species, denoted "species 1", was observed at low pH values. Species 1 was ascribed to a six-coordinate Mo(V
In our previous study of the fatal R160Q mutant of human sulfite oxidase (hSO) at low pH (Astashkin et al. J. Am. Chem. Soc.2008, 130, 8471- …
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