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Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia.
Bhatt DL, Steg PG, Miller M, Brinton EA, Jacobson TA, Ketchum SB, Doyle RT Jr, Juliano RA, Jiao L, Granowitz C, Tardif JC, Ballantyne CM; REDUCE-IT Investigators. Bhatt DL, et al. N Engl J Med. 2019 Jan 3;380(1):11-22. doi: 10.1056/NEJMoa1812792. Epub 2018 Nov 10. N Engl J Med. 2019. PMID: 30415628 Clinical Trial.
Fabrication and characterization of fish gelatin-based magnetic nanocomposite for biomedical applications.
Venupriya V, Krishnaveni V, Ramya M. Venupriya V, et al. World J Microbiol Biotechnol. 2023 Dec 2;40(1):23. doi: 10.1007/s11274-023-03800-3. World J Microbiol Biotechnol. 2023. PMID: 38040938
GMNC obtained at minimum gelatin concentration (6% w/v) produced well-dispersed sphere-shaped magnetite nanoparticles with an average particle size of 33 nm without aggregation. All three reported superparamagnetic behavior at 293 K. It also noted the highly biocompatible …
GMNC obtained at minimum gelatin concentration (6% w/v) produced well-dispersed sphere-shaped magnetite nanoparticles with an average partic …
Clinical and Genomic Evolution of Carbapenem-Resistant Klebsiella pneumoniae Bloodstream Infections over Two Time Periods at a Tertiary Care Hospital in South India: A Prospective Cohort Study.
Manesh A, Shankar C, George MM, Jasrotia DS, Lal B, George B, Mathews V, Eapen CE, Joseph P, Subramani K, Rao S, Peter JV, Chacko B, Zachariah A, Sathyendra S, Hansdak SG, Abraham OC, Iyadurai R, Vijayakumar S, Karthik R, Marwick CA, Parcell BJ, Gilbert IH, Veeraraghavan B, Varghese GM. Manesh A, et al. Infect Dis Ther. 2023 May;12(5):1319-1335. doi: 10.1007/s40121-023-00803-3. Epub 2023 Apr 16. Infect Dis Ther. 2023. PMID: 37062023 Free PMC article.
Recombinant engineered phage-derived enzybiotic in Pichia pastoris X-33 as whole cell biocatalyst for effective biocontrol of Vibrio parahaemolyticus in aquaculture.
Srinivasan R, Chaitanyakumar A, Subramanian P, Mageswari A, Gomathi A, Aswini V, Sankar AM, Ramya M, Gothandam KM. Srinivasan R, et al. Int J Biol Macromol. 2020 Jul 1;154:1576-1585. doi: 10.1016/j.ijbiomac.2019.11.042. Epub 2019 Nov 9. Int J Biol Macromol. 2020. PMID: 31715237
Vplys60 manifested stable activity over broad range of pH (6-10), temperatures (37-75 C) and salinity (100-600 mM NaCl). Biochemical and in silico analysis revealed that addition of calcium ion (Ca(2+)) enhanced the lytic activity of Vplys60 whereas other metal ions inhibi …
Vplys60 manifested stable activity over broad range of pH (6-10), temperatures (37-75 C) and salinity (100-600 mM NaCl). Biochemical …
Conformational stability of legume lectins reflect their different modes of quaternary association: solvent denaturation studies on concanavalin A and winged bean acidic agglutinin.
Mitra N, Srinivas VR, Ramya TN, Ahmad N, Reddy GB, Surolia A. Mitra N, et al. Biochemistry. 2002 Jul 23;41(29):9256-63. doi: 10.1021/bi020240m. Biochemistry. 2002. PMID: 12119041
As expected, the change in heat capacity upon unfolding was similar for both proteins at 3.5 and 3.7 kcal mol(-1) K(-1) for Concanavalin A and WBA II, respectively. Although the deltaG(H20) at the maximum stability of both proteins is around 16 kcal/mol, Concanavalin A exh …
As expected, the change in heat capacity upon unfolding was similar for both proteins at 3.5 and 3.7 kcal mol(-1) K(-1) for Concanava …
Iodine-mediated one-pot intramolecular decarboxylation domino reaction for accessing functionalised 2-(1,3,4-oxadiazol-2-yl)anilines with carbonic anhydrase inhibitory action.
Angapelly S, Ramya PVS, Sodhi R, Angeli A, Rangan K, Nagesh N, Supuran CT, Arifuddin M. Angapelly S, et al. J Enzyme Inhib Med Chem. 2018 Dec;33(1):615-628. doi: 10.1080/14756366.2018.1443447. J Enzyme Inhib Med Chem. 2018. PMID: 29536768 Free PMC article.
The prominent feature of this domino process involves consecutive condensation, hydrolytic ring cleavage, and an intramolecular decarboxylation, in a one-pot process that leads to the oxidative formation of a C-O bond. Fluorescence properties of some of the representative …
The prominent feature of this domino process involves consecutive condensation, hydrolytic ring cleavage, and an intramolecular decarboxylat …