Autism-Associated Vigilin Depletion Impairs DNA Damage Repair.
Banday S, Pandita RK, Mushtaq A, Bacolla A, Mir US, Singh DK, Jan S, Bhat KP, Hunt CR, Rao G, Charaka VK, Tainer JA, Pandita TK, Altaf M.
Banday S, et al.
Mol Cell Biol. 2021 Jun 23;41(7):e0008221. doi: 10.1128/MCB.00082-21. Epub 2021 Jun 23.
Mol Cell Biol. 2021.
PMID: 33941620
Free PMC article.
Conserved from yeast to humans, vigilin is an RNA-binding protein with 14 tandemly arranged nonidentical hnRNP K-type homology (KH) domains. Here, we report that vigilin depletion increased cell sensitivity to cisplatin- or ionizing radiation (IR)-induced cell death and ge …
Conserved from yeast to humans, vigilin is an RNA-binding protein with 14 tandemly arranged nonidentical hnRNP K-type homology (KH) d …