Lymphatic migration of unconventional T cells promotes site-specific immunity in distinct lymph nodes.
Ataide MA, Knöpper K, Cruz de Casas P, Ugur M, Eickhoff S, Zou M, Shaikh H, Trivedi A, Grafen A, Yang T, Prinz I, Ohlsen K, Gomez de Agüero M, Beilhack A, Huehn J, Gaya M, Saliba AE, Gasteiger G, Kastenmüller W.
Ataide MA, et al.
Immunity. 2022 Oct 11;55(10):1813-1828.e9. doi: 10.1016/j.immuni.2022.07.019. Epub 2022 Aug 23.
Immunity. 2022.
PMID: 36002023
Here, using LN transplantation, single-cell RNA-seq, spectral flow cytometry, and a transgenic mouse model for photolabeling, we showed that tissue-derived unconventional T cells (UTCs) migrate via the lymphatic route to locally draining LNs. As each tissue harbored a dist …
Here, using LN transplantation, single-cell RNA-seq, spectral flow cytometry, and a transgenic mouse model for photolabeling, we showed that …