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A thermosensitive PCNA allele underlies an ataxia-telangiectasia-like disorder.
Magrino J, Munford V, Martins DJ, Homma TK, Page B, Gaubitz C, Freire BL, Lerario AM, Vilar JB, Amorin A, Leão EKE, Kok F, Menck CF, Jorge AA, Kelch BA. Magrino J, et al. J Biol Chem. 2023 May;299(5):104656. doi: 10.1016/j.jbc.2023.104656. Epub 2023 Mar 27. J Biol Chem. 2023. PMID: 36990216 Free PMC article.
Mutational signatures and increased retrotransposon insertions in xeroderma pigmentosum variant skin tumors.
Corradi C, Vilar JB, Buzatto VC, de Souza TA, Castro LP, Munford V, De Vecchi R, Galante PAF, Orpinelli F, Miller TLA, Buzzo JL, Sotto MN, Saldiva P, de Oliveira JW, Chaibub SCW, Sarasin A, Menck CFM. Corradi C, et al. Among authors: vilar jb. Carcinogenesis. 2023 Aug 18;44(6):511-524. doi: 10.1093/carcin/bgad030. Carcinogenesis. 2023. PMID: 37195263
Localization matters: nuclear-trapped Survivin sensitizes glioblastoma cells to temozolomide by elevating cellular senescence and impairing homologous recombination.
Reich TR, Schwarzenbach C, Vilar JB, Unger S, Mühlhäusler F, Nikolova T, Poplawski A, Baymaz HI, Beli P, Christmann M, Tomicic MT. Reich TR, et al. Cell Mol Life Sci. 2021 Jul;78(14):5587-5604. doi: 10.1007/s00018-021-03864-0. Epub 2021 Jun 8. Cell Mol Life Sci. 2021. PMID: 34100981 Free PMC article.