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Biological activity of Morita-Baylis-Hillman adduct homodimers in L. infantum and L. amazonensis: anti-Leishmania activity and cytotoxicity.
da Câmara Rocha J, da Franca Rodrigues KA, do Nascimento Néris PL, da Silva LV, Almeida FS, Lima VS, Peixoto RF, da Câmara Rocha J, de Azevedo FLAA, Veras RC, de Medeiros IA, da Silva WAV, Lima-Junior CG, de Almeida Vasconcellos MLA, do Amaral IPG, de Oliveira MR, de Souza Lima Keesen T. da Câmara Rocha J, et al. Parasitol Res. 2019 Oct;118(10):3067-3076. doi: 10.1007/s00436-019-06403-w. Epub 2019 Aug 7. Parasitol Res. 2019. PMID: 31392413
2-Amino-thiophene derivatives present antileishmanial activity mediated by apoptosis and immunomodulation in vitro.
Rodrigues KA, Dias CN, Néris PL, Rocha Jda C, Scotti MT, Scotti L, Mascarenhas SR, Veras RC, de Medeiros IA, Keesen Tde S, de Oliveira TB, de Lima Mdo C, Balliano TL, de Aquino TM, de Moura RO, Mendonça Junior FJ, de Oliveira MR. Rodrigues KA, et al. Among authors: rocha jda c. Eur J Med Chem. 2015 Dec 1;106:1-14. doi: 10.1016/j.ejmech.2015.10.011. Epub 2015 Oct 17. Eur J Med Chem. 2015. PMID: 26513640
Synthesis of 16 New Hybrids from Tetrahydropyrans Derivatives and Morita-Baylis-Hillman Adducts: In Vitro Screening against Leishmania donovani.
Sousa SC, Rocha JD, Keesen TS, Silva ED, de Assis PA, de Oliveira JP, Capim SL, Xavier FJ, Marinho BG, Silva FP, Lima-Junior CG, Vasconcellos ML. Sousa SC, et al. Among authors: rocha jd. Molecules. 2017 Jan 30;22(2):207. doi: 10.3390/molecules22020207. Molecules. 2017. PMID: 28146095 Free PMC article.
Synthesis of New Cyclic Imides Derived from Safrole, Structure- and Ligand-based Approaches to Evaluate Potential New Multitarget Agents Against Species of Leishmania.
de Sousa Luis JA, da Silva Costa NA, Luis CCS, Lira BF, Athayde-Filho PF, de Souza Lima TK, da Câmara Rocha J, Scotti L, Scotti MT. de Sousa Luis JA, et al. Among authors: da camara rocha j. Med Chem. 2020;16(1):39-51. doi: 10.2174/1573406415666190430144950. Med Chem. 2020. PMID: 31208311