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Page 1
Homologous Recombination as a Fundamental Genome Surveillance Mechanism during DNA Replication.
Genes (Basel). 2021 Dec 9;12(12):1960. doi: 10.3390/genes12121960.
Genes (Basel). 2021.
PMID: 34946909
Free PMC article.
Review.
Homology-directed repair protects the replicating genome from metabolic assaults.
Somyajit K, Spies J, Coscia F, Kirik U, Rask MB, Lee JH, Neelsen KJ, Mund A, Jensen LJ, Paull TT, Mann M, Lukas J.
Somyajit K, et al. Among authors: spies j.
Dev Cell. 2021 Feb 22;56(4):461-477.e7. doi: 10.1016/j.devcel.2021.01.011.
Dev Cell. 2021.
PMID: 33621493
Free article.
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53BP1 nuclear bodies enforce replication timing at under-replicated DNA to limit heritable DNA damage.
Spies J, Lukas C, Somyajit K, Rask MB, Lukas J, Neelsen KJ.
Spies J, et al.
Nat Cell Biol. 2019 Apr;21(4):487-497. doi: 10.1038/s41556-019-0293-6. Epub 2019 Feb 25.
Nat Cell Biol. 2019.
PMID: 30804506
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Rad54 Phosphorylation Promotes Homologous Recombination by Balancing Rad54 Mobility and DNA Binding.
Lengert N, Spies J, Drossel B.
Lengert N, et al. Among authors: spies j.
Biophys J. 2019 Apr 23;116(8):1406-1419. doi: 10.1016/j.bpj.2019.03.001. Epub 2019 Mar 19.
Biophys J. 2019.
PMID: 30961891
Free PMC article.
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Nek1 Regulates Rad54 to Orchestrate Homologous Recombination and Replication Fork Stability.
Spies J, Waizenegger A, Barton O, Sürder M, Wright WD, Heyer WD, Löbrich M.
Spies J, et al.
Mol Cell. 2016 Jun 16;62(6):903-917. doi: 10.1016/j.molcel.2016.04.032. Epub 2016 Jun 2.
Mol Cell. 2016.
PMID: 27264870
Free PMC article.
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DNA Double-Strand Break Resection Occurs during Non-homologous End Joining in G1 but Is Distinct from Resection during Homologous Recombination.
Biehs R, Steinlage M, Barton O, Juhász S, Künzel J, Spies J, Shibata A, Jeggo PA, Löbrich M.
Biehs R, et al. Among authors: spies j.
Mol Cell. 2017 Feb 16;65(4):671-684.e5. doi: 10.1016/j.molcel.2016.12.016. Epub 2017 Jan 26.
Mol Cell. 2017.
PMID: 28132842
Free PMC article.
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