Functional screening of selective mitochondrial inhibitors of Plasmodium.
Gomez-Lorenzo MG, Rodríguez-Alejandre A, Moliner-Cubel S, Martínez-Hoyos M, Bahamontes-Rosa N, Gonzalez Del Rio R, Ródenas C, Fuente J, Lavandera JL, García-Bustos JF, Mendoza-Losana A.
Gomez-Lorenzo MG, et al.
Int J Parasitol Drugs Drug Resist. 2018 Aug;8(2):295-303. doi: 10.1016/j.ijpddr.2018.04.007. Epub 2018 May 9.
Int J Parasitol Drugs Drug Resist. 2018.
PMID: 29775797
Free PMC article.
Here we describe a whole-cell method to detect inhibitors of the mitochondrial electron transport chain, using oxygen consumption as high throughput readout in 384-well plate format. The usefulness of the method has been confirmed with the Tres Cantos Antimalarial Compound …
Here we describe a whole-cell method to detect inhibitors of the mitochondrial electron transport chain, using oxygen consumption as high th …