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The CCR6/CCL20 axis expands RORγt+ Tregs to protect from glomerulonephritis.
Herrnstadt GR, Niehus CB, Ramcke T, Hagenstein J, Ehnold LI, Nosko A, Warkotsch MT, Feindt FC, Melderis S, Paust HJ, Sivayoganathan V, Jauch-Speer SL, Wong MN, Indenbirken D, Krebs CF, Huber TB, Panzer U, Puelles VG, Kluger MA, Steinmetz OM. Herrnstadt GR, et al. Among authors: hagenstein j. Kidney Int. 2023 Jul;104(1):74-89. doi: 10.1016/j.kint.2023.02.027. Epub 2023 Mar 15. Kidney Int. 2023. PMID: 36924892
An antigen-specific chimeric autoantibody receptor (CAAR) NK cell strategy for the elimination of anti-PLA2R1 and anti-THSD7A antibody-secreting cells.
Seifert L, Riecken K, Zahner G, Hambach J, Hagenstein J, Dubberke G, Huber TB, Koch-Nolte F, Fehse B, Tomas NM. Seifert L, et al. Among authors: hagenstein j. Kidney Int. 2024 Apr;105(4):886-889. doi: 10.1016/j.kint.2024.01.021. Epub 2024 Feb 2. Kidney Int. 2024. PMID: 38309682 Free article. No abstract available.
Amphiregulin Aggravates Glomerulonephritis via Recruitment and Activation of Myeloid Cells.
Melderis S, Hagenstein J, Warkotsch MT, Dang J, Herrnstadt GR, Niehus CB, Neumann K, Panzer U, Berasain C, Avila MA, Tharaux PL, Tiegs G, Steinmetz OM. Melderis S, et al. Among authors: hagenstein j. J Am Soc Nephrol. 2020 Sep;31(9):1996-2012. doi: 10.1681/ASN.2019111215. Epub 2020 Jul 2. J Am Soc Nephrol. 2020. PMID: 32616537 Free PMC article.
The Amphiregulin/EGFR axis protects from lupus nephritis via downregulation of pathogenic CD4+ T helper cell responses.
Melderis S, Warkotsch MT, Dang J, Hagenstein J, Ehnold LI, Herrnstadt GR, Niehus CB, Feindt FC, Kylies D, Puelles VG, Berasain C, Avila MA, Neumann K, Tiegs G, Huber TB, Tharaux PL, Steinmetz OM. Melderis S, et al. Among authors: hagenstein j. J Autoimmun. 2022 May;129:102829. doi: 10.1016/j.jaut.2022.102829. Epub 2022 Apr 22. J Autoimmun. 2022. PMID: 35468361