Refeeding syndrome in Southeastern Taiwan: our experience with 11 cases

World J Gastroenterol. 2014 Aug 14;20(30):10525-30. doi: 10.3748/wjg.v20.i30.10525.

Abstract

Aim: To present our experience with refeeding syndrome in southeastern Taiwan.

Methods: We conducted a retrospective study during a 2-year period at the Mackay Memorial Hospital, Taitung Branch. We enrolled patients with very little or no nutrition intake for more than 10 d, a high risk group of refeeding syndrome, including those suffering from alcohol abuse, cancerous cachexia, chronic malnutrition, and prolonged starvation.

Results: A total of 11 patients (7 males, 4 females) with nasogastric feeding were included as having refeeding syndrome. Most of them had the symptoms of diarrhea, lethargy, and leg edema. The initial nutritional supplement was found to be relatively high in calories (1355.1 ± 296.2 kcal/d), high in protein (47.3 ± 10.4 gm/d), low in vitamin B1 (2.0 ± 0.5 mg/d), low in potassium (1260.4 ± 297.7 mg/d), and low in phosphorus (660.1 ± 151.8 mg/d). Furthermore, hypophosphatemia (2.4 ± 0.9 mg/dL) was noted during follow-up. Based on the suggestions of a dietician and a gastroenterologist, the clinical disorders of diarrhea, malaise and leg edema were significantly improved. The level of phosphate was also increased (3.3 ± 0.6 mg/dL).

Conclusion: Refeeding syndrome is an overlooked and risky disorder that has some potentially fatal complications. Nasogastric feeding in nursing homes is an important risk factor for patients and deserves greater attention based on the initial results of this study.

Keywords: Cachexia; Hypophosphatemia; Nutrition status; Refeeding syndrome; Risk assessment.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Enteral Nutrition / adverse effects*
  • Female
  • Humans
  • Intubation, Gastrointestinal
  • Male
  • Malnutrition / diagnosis
  • Malnutrition / physiopathology
  • Malnutrition / therapy*
  • Middle Aged
  • Nutritional Status
  • Parenteral Nutrition, Total / adverse effects*
  • Refeeding Syndrome / diagnosis
  • Refeeding Syndrome / etiology*
  • Refeeding Syndrome / physiopathology
  • Refeeding Syndrome / therapy
  • Retrospective Studies
  • Risk Assessment
  • Risk Factors
  • Taiwan
  • Treatment Outcome