Background: Corneal and conjunctival calcification have been associated with chronic renal failure and hyperparathyroidism. Corneal alterations include band keratopathy and/or limbal involvement similar to limbal girdle of Vogt. Conjunctival lesions resemble pingueculae. Lid lesions, which include calcified deposits adjacent to the meibomian gland orifices, are much less common.
Case report: A 52-year-old woman came to SUNY State College of Optometry clinic with a medical history of gestational hypertension, which led to chronic kidney failure and secondary hyperparathyroidism. Slit-lamp examination revealed multiple small, white, round calcium deposits, which were found just posterior to the Meibomian gland orifices, along the superior and inferior lid margins.
Conclusion: Ocular calcification has been observed in patients with certain systemic diseases such as chronic renal failure, hyperparathyroidism, hypophosphonemia, sarcoidosis, hypervitaminosis D, and metastatic neoplasia. We present the third report of eyelid calcification associated with a systemic disease.