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Novel inhibitors of human glucose-6-phosphate dehydrogenase (HsG6PD) affect the activity and stability of the protein.
Ramírez-Nava EJ, Hernández-Ochoa B, Navarrete-Vázquez G, Arreguín-Espinosa R, Ortega-Cuellar D, González-Valdez A, Martínez-Rosas V, Morales-Luna L, Martínez-Miranda J, Sierra-Palacios E, Rocha-Ramírez LM, De Franceschi L, Marcial-Quino J, Gómez-Manzo S. Ramírez-Nava EJ, et al. Among authors: martinez miranda j. Biochim Biophys Acta Gen Subj. 2021 Mar;1865(3):129828. doi: 10.1016/j.bbagen.2020.129828. Epub 2020 Dec 23. Biochim Biophys Acta Gen Subj. 2021. PMID: 33347959
Design, Synthesis, and In Silico Multitarget Pharmacological Simulations of Acid Bioisosteres with a Validated In Vivo Antihyperglycemic Effect.
Domínguez-Mendoza EA, Galván-Ciprés Y, Martínez-Miranda J, Miranda-González C, Colín-Lozano B, Hernández-Núñez E, Hernández-Bolio GI, Palomino-Hernández O, Navarrete-Vazquez G. Domínguez-Mendoza EA, et al. Among authors: martinez miranda j. Molecules. 2021 Feb 4;26(4):799. doi: 10.3390/molecules26040799. Molecules. 2021. PMID: 33557136 Free PMC article.