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PD-L1 and PD-L2 Expression in Cervical Cancer: Regulation and Biomarker Potential.
Rotman J, den Otter LAS, Bleeker MCG, Samuels SS, Heeren AM, Roemer MGM, Kenter GG, Zijlmans HJMAA, van Trommel NE, de Gruijl TD, Jordanova ES. Rotman J, et al. Front Immunol. 2020 Dec 17;11:596825. doi: 10.3389/fimmu.2020.596825. eCollection 2020. Front Immunol. 2020. PMID: 33424844 Free PMC article.
Delta-Like Ligand-Notch1 Signaling Is Selectively Modulated by HPV16 E6 to Promote Squamous Cell Proliferation and Correlates with Cervical Cancer Prognosis.
Khelil M, Griffin H, Bleeker MCG, Steenbergen RDM, Zheng K, Saunders-Wood T, Samuels S, Rotman J, Vos W, van den Akker BE, de Menezes RX, Kenter GG, Doorbar J, Jordanova ES. Khelil M, et al. Among authors: rotman j. Cancer Res. 2021 Apr 1;81(7):1909-1921. doi: 10.1158/0008-5472.CAN-20-1996. Epub 2021 Jan 26. Cancer Res. 2021. PMID: 33500246
HPV-16 E6/E7 DNA tattoo vaccination using genetically optimized vaccines elicit clinical and immunological responses in patients with usual vulvar intraepithelial neoplasia (uVIN): a phase I/II clinical trial.
Bakker NAM, Rotman J, van Beurden M, Zijlmans HJM, van Ruiten M, Samuels S, Nuijen B, Beijnen J, De Visser K, Haanen J, Schumacher T, de Gruijl TD, Jordanova ES, Kenter GG, van den Berg JH, van Trommel NE. Bakker NAM, et al. Among authors: rotman j. J Immunother Cancer. 2021 Aug;9(8):e002547. doi: 10.1136/jitc-2021-002547. J Immunother Cancer. 2021. PMID: 34341131 Free PMC article. Clinical Trial.
Adenocarcinoma of the Uterine Cervix Shows Impaired Recruitment of cDC1 and CD8+ T Cells and Elevated β-Catenin Activation Compared with Squamous Cell Carcinoma.
Rotman J, Heeren AM, Gassama AA, Lougheed SM, Pocorni N, Stam AGM, Bleeker MCG, Zijlmans HJMAA, Mom CH, Kenter GG, Jordanova ES, de Gruijl TD. Rotman J, et al. Clin Cancer Res. 2020 Jul 15;26(14):3791-3802. doi: 10.1158/1078-0432.CCR-19-3826. Epub 2020 Mar 27. Clin Cancer Res. 2020. PMID: 32220890