Immunological Assays used to Support Efficacy of Zika Virus Vaccines

Kenneth H Eckels; Rafael A De La Barrera; Joseph Robert Putnak

doi:10.3390/tropicalmed4030097

Immunological Assays used to Support Efficacy of Zika Virus Vaccines

Trop Med Infect Dis. 2019 Jun 28;4(3):97. doi: 10.3390/tropicalmed4030097.

Authors

Kenneth H Eckels¹, Rafael A De La Barrera², Joseph Robert Putnak²

Affiliations

¹ Walter Reed Army Institute of Research, 503 Robert Grant Ave., Silver Spring, MD 20910, USA. kenneth.h.eckels.ctr@mail.mil.
² Walter Reed Army Institute of Research, 503 Robert Grant Ave., Silver Spring, MD 20910, USA.

Abstract

In February of 2016, the World Health Organization (WHO) declared Zika virus (ZIKV) a Public Health Emergency of International Concern. This prompted a rapid response from both the private and public sector resulting in the generation of several promising vaccine candidates. In this review, we discuss published scientific efforts associated with these novel vaccines, emphasizing the immunological assays used to evaluate their immunogenicity and efficacy, and support future licensure.

Keywords: Zika; assays; vaccine; virus.

Publication types

Review