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Page 1
Discovery of an Oral, Beyond-Rule-of-Five Mcl-1 Protein-Protein Interaction Modulator with the Potential of Treating Hematological Malignancies.
Romanov-Michailidis F, Hsiao CC, Urner LM, Jerhaoui S, Surkyn M, Miller B, Vos A, Dominguez Blanco M, Bueters R, Vinken P, Bekkers M, Walker D, Pietrak B, Eyckmans W, Dores-Sousa JL, Joo Koo S, Lento W, Bauser M, Philippar U, Rombouts FJR. Romanov-Michailidis F, et al. Among authors: dores sousa jl. J Med Chem. 2023 May 11;66(9):6122-6148. doi: 10.1021/acs.jmedchem.2c01953. Epub 2023 Apr 28. J Med Chem. 2023. PMID: 37114951
Inflammation as a Possible Trigger for Mitoxantrone-Induced Cardiotoxicity: An In Vivo Study in Adult and Infant Mice.
Reis-Mendes A, Dores-Sousa JL, Padrão AI, Duarte-Araújo M, Duarte JA, Seabra V, Gonçalves-Monteiro S, Remião F, Carvalho F, Sousa E, Bastos ML, Costa VM. Reis-Mendes A, et al. Among authors: dores sousa jl. Pharmaceuticals (Basel). 2021 May 26;14(6):510. doi: 10.3390/ph14060510. Pharmaceuticals (Basel). 2021. PMID: 34073506 Free PMC article.
Mitoxantrone impairs proteasome activity and prompts early energetic and proteomic changes in HL-1 cardiomyocytes at clinically relevant concentrations.
Costa VM, Capela JP, Sousa JR, Eleutério RP, Rodrigues PRS, Dores-Sousa JL, Carvalho RA, Lourdes Bastos M, Duarte JA, Remião F, Almeida MG, Varner KJ, Carvalho F. Costa VM, et al. Among authors: dores sousa jl. Arch Toxicol. 2020 Dec;94(12):4067-4084. doi: 10.1007/s00204-020-02874-4. Epub 2020 Sep 7. Arch Toxicol. 2020. PMID: 32894303
13 results