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Peptide-conjugated antimiRs improve myotonic dystrophy type 1 phenotypes by promoting endogenous MBNL1 expression.
González-Martínez I, Cerro-Herreros E, Moreno N, García-Rey A, Espinosa-Espinosa J, Carrascosa-Sàez M, Piqueras-Losilla D, Arzumanov A, Seoane-Miraz D, Jad Y, Raz R, Wood MJ, Varela MA, Llamusí B, Artero R. González-Martínez I, et al. Among authors: espinosa espinosa j. Mol Ther Nucleic Acids. 2023 Sep 5;34:102024. doi: 10.1016/j.omtn.2023.09.001. eCollection 2023 Dec 12. Mol Ther Nucleic Acids. 2023. PMID: 37744174 Free PMC article.
BlockmiR AONs as Site-Specific Therapeutic MBNL Modulation in Myotonic Dystrophy 2D and 3D Muscle Cells and HSALR Mice.
Overby SJ, Cerro-Herreros E, Espinosa-Espinosa J, González-Martínez I, Moreno N, Fernández-Costa JM, Balaguer-Trias J, Ramón-Azcón J, Pérez-Alonso M, Møller T, Llamusí B, Artero R. Overby SJ, et al. Among authors: espinosa espinosa j. Pharmaceutics. 2023 Mar 31;15(4):1118. doi: 10.3390/pharmaceutics15041118. Pharmaceutics. 2023. PMID: 37111604 Free PMC article.
CRISPR-Cas9 editing of a TNPO3 mutation in a muscle cell model of limb-girdle muscular dystrophy type D2.
Poyatos-García J, Blázquez-Bernal Á, Selva-Giménez M, Bargiela A, Espinosa-Espinosa J, Vázquez-Manrique RP, Bigot A, Artero R, Vilchez JJ. Poyatos-García J, et al. Among authors: espinosa espinosa j. Mol Ther Nucleic Acids. 2023 Jan 11;31:324-338. doi: 10.1016/j.omtn.2023.01.004. eCollection 2023 Mar 14. Mol Ther Nucleic Acids. 2023. PMID: 36789274 Free PMC article.
Preclinical characterization of antagomiR-218 as a potential treatment for myotonic dystrophy.
Cerro-Herreros E, González-Martínez I, Moreno N, Espinosa-Espinosa J, Fernández-Costa JM, Colom-Rodrigo A, Overby SJ, Seoane-Miraz D, Poyatos-García J, Vilchez JJ, López de Munain A, Varela MA, Wood MJ, Pérez-Alonso M, Llamusí B, Artero R. Cerro-Herreros E, et al. Among authors: espinosa espinosa j. Mol Ther Nucleic Acids. 2021 Jul 29;26:174-191. doi: 10.1016/j.omtn.2021.07.017. eCollection 2021 Dec 3. Mol Ther Nucleic Acids. 2021. PMID: 34513303 Free PMC article.