A novel imaging platform for non-invasive screening of abnormal glucose tolerance

Diabetes Res Clin Pract. 2016 Jun:116:83-5. doi: 10.1016/j.diabres.2016.03.014. Epub 2016 Apr 23.

Abstract

Optical measurement of skin auto-fluorescence (SAF), most likely emanating from accumulated advanced glycation end-products (AGEs), has been proposed for the noninvasive diagnosis of glucose intolerance in clinical settings. Here, we developed a novel imaging system with transmission geometry for SAF measurement and compared its diagnostic performance in a Korean population.

Keywords: AGE; Diagnosis; Glucose intolerance; Noninvasive; Skin auto-fluorescence.

MeSH terms

  • Adult
  • Aged
  • Female
  • Glucose Intolerance / diagnostic imaging*
  • Glycation End Products, Advanced / metabolism
  • Humans
  • Hyperglycemia / diagnostic imaging*
  • Male
  • Mass Screening / methods
  • Middle Aged
  • Optical Imaging / methods*
  • Sensitivity and Specificity
  • Skin / metabolism*
  • Spectrometry, Fluorescence / methods*

Substances

  • Glycation End Products, Advanced