Impact of COVID-19 outbreak on ischemic stroke admissions and in-hospital mortality in North-West Spain

Int J Stroke. 2020 Oct;15(7):755-762. doi: 10.1177/1747493020938301. Epub 2020 Jun 26.

Abstract

Background and purpose: Spain has been one of the countries heavily stricken by COVID-19. But this epidemic has not affected all regions equally. We analyzed the impact of the COVID-19 pandemic on hospital stroke admissions and in-hospital mortality in tertiary referral hospitals from North-West Spain.

Methods: Spanish multicenter retrospective observational study based on data from tertiary hospitals of the NORDICTUS network. We recorded the number of patients admitted for ischemic stroke between 30 December 2019 and 3 May 2020, the number of IVT and EVT procedures, and in-hospital mortality.

Results: In the study period, 2737 patients were admitted with ischemic stroke. There was a decrease in the weekly mean admitted patients during the pandemic (124 vs. 173, p<0.001). In-hospital mortality of stroke patients increased significantly (9.9% vs. 6.5%, p = 0.003), but there were no differences in the proportion of IVT (17.3% vs. 16.1%, p = 0.405) or EVT (22% vs. 23%, p = 0.504).

Conclusion: We found a decrease in the number of ischemic stroke admissions and an increase in in-hospital mortality during the COVID-19 epidemic in this large study from North-West Spain. There were regional changes within the network, not fully explained by the severity of the pandemic in different regions.

Keywords: COVID-19; Spain; Stroke; ischemic stroke; mortality; stroke care.

Publication types

  • Multicenter Study
  • Observational Study

MeSH terms

  • Aged
  • Betacoronavirus*
  • Brain Ischemia / diagnosis
  • Brain Ischemia / mortality*
  • Brain Ischemia / therapy
  • COVID-19
  • Coronavirus Infections / epidemiology*
  • Female
  • Hospital Mortality
  • Hospitalization / statistics & numerical data*
  • Humans
  • Male
  • Pandemics
  • Pneumonia, Viral / epidemiology*
  • Reperfusion
  • Retrospective Studies
  • SARS-CoV-2
  • Spain
  • Stroke / diagnosis
  • Stroke / mortality*
  • Stroke / therapy
  • Tertiary Care Centers