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Ceramides bind VDAC2 to trigger mitochondrial apoptosis.
Dadsena S, Bockelmann S, Mina JGM, Hassan DG, Korneev S, Razzera G, Jahn H, Niekamp P, Müller D, Schneider M, Tafesse FG, Marrink SJ, Melo MN, Holthuis JCM. Dadsena S, et al. Among authors: mina jgm. Nat Commun. 2019 Apr 23;10(1):1832. doi: 10.1038/s41467-019-09654-4. Nat Commun. 2019. PMID: 31015432 Free PMC article.
Tamoxifen inhibits the biosynthesis of inositolphosphorylceramide in Leishmania.
Trinconi CT, Miguel DC, Silber AM, Brown C, Mina JGM, Denny PW, Heise N, Uliana SRB. Trinconi CT, et al. Among authors: mina jgm. Int J Parasitol Drugs Drug Resist. 2018 Dec;8(3):475-487. doi: 10.1016/j.ijpddr.2018.10.007. Epub 2018 Oct 24. Int J Parasitol Drugs Drug Resist. 2018. PMID: 30399513 Free PMC article.
Antileishmanial Chemotherapy through Clemastine Fumarate Mediated Inhibition of the Leishmania Inositol Phosphorylceramide Synthase.
Mina JGM, Charlton RL, Alpizar-Sosa E, Escrivani DO, Brown C, Alqaisi A, Borsodi MPG, Figueiredo CP, de Lima EV, Dickie EA, Wei W, Coutinho-Silva R, Merritt A, Smith TK, Barrett MP, Rossi-Bergmann B, Denny PW, Steel PG. Mina JGM, et al. ACS Infect Dis. 2021 Jan 8;7(1):47-63. doi: 10.1021/acsinfecdis.0c00546. Epub 2020 Dec 8. ACS Infect Dis. 2021. PMID: 33291887 Free PMC article.
11 results