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Simvastatin in the acute respiratory distress syndrome.
McAuley DF, Laffey JG, O'Kane CM, Perkins GD, Mullan B, Trinder TJ, Johnston P, Hopkins PA, Johnston AJ, McDowell C, McNally C; HARP-2 Investigators; Irish Critical Care Trials Group. McAuley DF, et al. N Engl J Med. 2014 Oct 30;371(18):1695-703. doi: 10.1056/NEJMoa1403285. Epub 2014 Sep 30. N Engl J Med. 2014. PMID: 25268516 Free article. Clinical Trial.
The ratio of morning cortisol to CRP prospectively predicts first-onset depression in at-risk adolescents.
Landau ER, Raniti MB, Blake M, Waloszek JM, Blake L, Simmons JG, Schwartz O, Murray G, Trinder J, Allen NB, Byrne ML. Landau ER, et al. Soc Sci Med. 2021 Jul;281:114098. doi: 10.1016/j.socscimed.2021.114098. Epub 2021 Jun 4. Soc Sci Med. 2021. PMID: 34126291 Clinical Trial.
Increasingly, dysregulated levels of immune and neuroendocrine markers, such as C-reactive protein (CRP) and cortisol, have been demonstrated as both precursors to and consequences of depression. ...
Increasingly, dysregulated levels of immune and neuroendocrine markers, such as C-reactive protein (CRP) and cortisol, have been demo …
CETP genetic variant rs1800777 (allele A) is associated with abnormally low HDL-C levels and increased risk of AKI during sepsis.
Genga KR, Trinder M, Kong HJ, Li X, Leung AKK, Shimada T, Walley KR, Russell JA, Francis GA, Brunham LR, Boyd JH. Genga KR, et al. Sci Rep. 2018 Nov 13;8(1):16764. doi: 10.1038/s41598-018-35261-2. Sci Rep. 2018. PMID: 30425299 Free PMC article.
High-density cholesterol (HDL-C) levels are influenced by genetic variation in several genes. ...We investigated whether genetic polymorphisms in ten genes known to regulate HDL-C levels are associated with both HDL-C levels and AKI development during sepsis. …
High-density cholesterol (HDL-C) levels are influenced by genetic variation in several genes. ...We investigated whether genetic poly …
Crucial role for lung iron level and regulation in the pathogenesis and severity of asthma.
Ali MK, Kim RY, Brown AC, Mayall JR, Karim R, Pinkerton JW, Liu G, Martin KL, Starkey MR, Pillar AL, Donovan C, Pathinayake PS, Carroll OR, Trinder D, Tay HL, Badi YE, Kermani NZ, Guo YK, Aryal R, Mumby S, Pavlidis S, Adcock IM, Weaver J, Xenaki D, Oliver BG, Holliday EG, Foster PS, Wark PA, Johnstone DM, Milward EA, Hansbro PM, Horvat JC. Ali MK, et al. Eur Respir J. 2020 Apr 23;55(4):1901340. doi: 10.1183/13993003.01340-2019. Print 2020 Apr. Eur Respir J. 2020. PMID: 32184317 Free article.
Fatal and Nonfatal Events Within 14 days After Early, Intensive Mobilization Poststroke.
Bernhardt J, Borschmann K, Collier JM, Thrift AG, Langhorne P, Middleton S, Lindley RI, Dewey HM, Bath P, Said CM, Churilov L, Ellery F, Bladin C, Reid CM, Frayne JH, Srikanth V, Read SJ, Donnan GA; AVERT Trialists Collaboration Group. Bernhardt J, et al. Neurology. 2021 Feb 22;96(8):e1156-e1166. doi: 10.1212/WNL.0000000000011106. Neurology. 2021. PMID: 33144512 Free PMC article.
Prespecified dose-response analysis for A Very Early Rehabilitation Trial (AVERT).
Bernhardt J, Churilov L, Ellery F, Collier J, Chamberlain J, Langhorne P, Lindley RI, Moodie M, Dewey H, Thrift AG, Donnan G; AVERT Collaboration Group. Bernhardt J, et al. Neurology. 2016 Jun 7;86(23):2138-45. doi: 10.1212/WNL.0000000000002459. Epub 2016 Feb 17. Neurology. 2016. PMID: 26888985 Free PMC article. Clinical Trial.