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Page 1
Conformational plasticity of ADAMTS13 in hemostasis and autoimmunity.
Ercig B, Arfman T, Hrdinova J, Wichapong K, Reutelingsperger CPM, Vanhoorelbeke K, Nicolaes GAF, Voorberg J. Ercig B, et al. Among authors: hrdinova j. J Biol Chem. 2021 Oct;297(4):101132. doi: 10.1016/j.jbc.2021.101132. Epub 2021 Aug 27. J Biol Chem. 2021. PMID: 34461090 Free PMC article. Review.
N-glycan-mediated shielding of ADAMTS13 prevents binding of pathogenic autoantibodies in immune-mediated TTP.
Ercig B, Graça NAG, Kangro K, Arfman T, Wichapong K, Hrdinová J, Kaijen P, van Alphen FPJ, van den Biggelaar M, Vanhoorelbeke K, Veyradier A, Coppo P, Reutelingsperger C, Nicolaes GAF, Männik A, Voorberg J. Ercig B, et al. Among authors: hrdinova j. Blood. 2021 May 13;137(19):2694-2698. doi: 10.1182/blood.2020007972. Blood. 2021. PMID: 33544829 Free PMC article.
Structure-Based Cyclic Glycoprotein Ibα-Derived Peptides Interfering with von Willebrand Factor-Binding, Affecting Platelet Aggregation under Shear.
Hrdinova J, Fernández DI, Ercig B, Tullemans BME, Suylen DPL, Agten SM, Jurk K, Hackeng TM, Vanhoorelbeke K, Voorberg J, Reutelingsperger CPM, Wichapong K, Heemskerk JWM, Nicolaes GAF. Hrdinova J, et al. Int J Mol Sci. 2022 Feb 12;23(4):2046. doi: 10.3390/ijms23042046. Int J Mol Sci. 2022. PMID: 35216161 Free PMC article.
The class I scavenger receptor CD163 promotes internalization of ADAMTS13 by macrophages.
Verbij FC, Sorvillo N, Kaijen PHP, Hrdinova J, Peyron I, Fijnheer R, Ten Brinke A, Meijer AB, van Alphen FPJ, van den Berg TK, Graversen JJH, Moestrup SK, Voorberg J. Verbij FC, et al. Among authors: hrdinova j. Blood Adv. 2017 Jan 16;1(5):293-305. doi: 10.1182/bloodadvances.2016001321. eCollection 2017 Jan 24. Blood Adv. 2017. PMID: 29296945 Free PMC article.