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2011 1
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21 results

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Page 1
Rivaroxaban versus warfarin in nonvalvular atrial fibrillation.
Patel MR, Mahaffey KW, Garg J, Pan G, Singer DE, Hacke W, Breithardt G, Halperin JL, Hankey GJ, Piccini JP, Becker RC, Nessel CC, Paolini JF, Berkowitz SD, Fox KA, Califf RM; ROCKET AF Investigators. Patel MR, et al. N Engl J Med. 2011 Sep 8;365(10):883-91. doi: 10.1056/NEJMoa1009638. Epub 2011 Aug 10. N Engl J Med. 2011. PMID: 21830957 Free article. Clinical Trial.
Specific detection of tau seeding activity in Alzheimer's disease using rationally designed biosensor cells.
Lathuiliere A, Jo Y, Perbet R, Donahue C, Commins C, Quittot N, Fan Z, Bennett RE, Hyman BT. Lathuiliere A, et al. Mol Neurodegener. 2023 Aug 8;18(1):53. doi: 10.1186/s13024-023-00643-2. Mol Neurodegener. 2023. PMID: 37553663 Free PMC article.
RESULTS: We performed the rational design of novel tau probes based on the current structural knowledge of pathological tau aggregates in Alzheimer's disease. We generated Forster resonance energy transfer (FRET)-based biosensor stable cell lines and characterized their se …
RESULTS: We performed the rational design of novel tau probes based on the current structural knowledge of pathological tau aggregates in Al …
Efficacy and safety of rivaroxaban compared with warfarin among elderly patients with nonvalvular atrial fibrillation in the Rivaroxaban Once Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF).
Halperin JL, Hankey GJ, Wojdyla DM, Piccini JP, Lokhnygina Y, Patel MR, Breithardt G, Singer DE, Becker RC, Hacke W, Paolini JF, Nessel CC, Mahaffey KW, Califf RM, Fox KA; ROCKET AF Steering Committee and Investigators. Halperin JL, et al. Circulation. 2014 Jul 8;130(2):138-46. doi: 10.1161/CIRCULATIONAHA.113.005008. Epub 2014 Jun 3. Circulation. 2014. PMID: 24895454 Free article. Clinical Trial.
Nanodiscoidal Nucleic Acids for Gene Regulation.
Sharma R, Narum S, Liu S, Dong Y, Baek KI, Jo H, Salaita K. Sharma R, et al. ACS Chem Biol. 2023 Nov 17;18(11):2349-2367. doi: 10.1021/acschembio.3c00038. Epub 2023 Nov 1. ACS Chem Biol. 2023. PMID: 37910400 Free PMC article.
NNAs showed superior nuclease resistance and enhanced cellular uptake that was mediated through the scavenger receptor B1. Time-dependent Forster resonance energy transfer (FRET) analysis of internalized NNA confirmed that NNAs display increased stability. ...
NNAs showed superior nuclease resistance and enhanced cellular uptake that was mediated through the scavenger receptor B1. Time-dependent …
Development of a Compensated Forster Resonance Energy Transfer Imaging for Improved Assessment of the Intrapulmonary Distribution of Polymeric Nanoparticles.
Togami K, Hazama Y, Nakamura Y, Ishizawa K, Chono S. Togami K, et al. J Pharm Sci. 2023 Oct;112(10):2696-2702. doi: 10.1016/j.xphs.2023.07.015. Epub 2023 Jul 20. J Pharm Sci. 2023. PMID: 37478971
It is essential to accurately evaluate the intrapulmonary behavior of nanoparticles to optimize drug delivery and achieve selective targeting of lung lesions. Prior research used the Forster resonance energy transfer (FRET) phenomenon to study the in vivo behavior of nanop …
It is essential to accurately evaluate the intrapulmonary behavior of nanoparticles to optimize drug delivery and achieve selective targetin …
Multiscale Live Imaging Using Forster Resonance Energy Transfer (FRET) for Evaluating the Biological Behavior of Nanoparticles as Drug Carriers.
Ishizawa K, Togami K, Tada H, Chono S. Ishizawa K, et al. J Pharm Sci. 2020 Dec;109(12):3608-3616. doi: 10.1016/j.xphs.2020.08.028. Epub 2020 Sep 11. J Pharm Sci. 2020. PMID: 32926888
In the present study, the biological behavior of polymeric nanoparticles was directly traced in living mice and cells. The dissociation of nanoparticles was detected by Forster resonance energy transfer (FRET) imaging. DiR and DiD were encapsulated in the nanoparticles for …
In the present study, the biological behavior of polymeric nanoparticles was directly traced in living mice and cells. The dissociation of n …
Predicting progression-free survival after systemic therapy in advanced head and neck cancer: Bayesian regression and model development.
Barber PR, Mustapha R, Flores-Borja F, Alfano G, Ng K, Weitsman G, Dolcetti L, Suwaidan AA, Wong F, Vicencio JM, Galazi M, Opzoomer JW, Arnold JN, Thavaraj S, Kordasti S, Doyle J, Greenberg J, Dillon MT, Harrington KJ, Forster M, Coolen ACC, Ng T. Barber PR, et al. Elife. 2022 Dec 23;11:e73288. doi: 10.7554/eLife.73288. Elife. 2022. PMID: 36562609 Free PMC article.
Development of visualization and analysis methods for evaluating intratumoral nanoparticle kinetics for tumor-targeted drug delivery using Forster resonance energy transfer in vivo live imaging and tissue clearing techniques.
Togami K, Ishizawa K, Yasuda M, Tada H, Chono S. Togami K, et al. J Pharm Biomed Anal. 2023 Jan 20;223:115127. doi: 10.1016/j.jpba.2022.115127. Epub 2022 Oct 28. J Pharm Biomed Anal. 2023. PMID: 36327577
In this study, the imaging methods for evaluating the kinetics of nanoparticles as drug delivery systems in tumor tissues were improved in BxPC3 tumor-bearing mice. First, Forster resonance energy transfer (FRET) live imaging was selected to quantitatively evaluate nanopar …
In this study, the imaging methods for evaluating the kinetics of nanoparticles as drug delivery systems in tumor tissues were improved in B …
21 results