Knuckle Pads Successfully Treated with 2% Crisaborole Ointment Combined with Triamcinolone Acetonide and Neomycin Plaster: A Case Report

Yimin Liang; Jingyao Liang; Qiongxiao Huang; Xin Tian; Lei Shao; Manqi Xia; Yumei Liu

doi:10.2147/CCID.S414268

Knuckle Pads Successfully Treated with 2% Crisaborole Ointment Combined with Triamcinolone Acetonide and Neomycin Plaster: A Case Report

Clin Cosmet Investig Dermatol. 2023 Jul 24:16:1893-1897. doi: 10.2147/CCID.S414268. eCollection 2023.

Authors

Yimin Liang^#¹, Jingyao Liang^#¹, Qiongxiao Huang¹, Xin Tian¹, Lei Shao¹, Manqi Xia¹, Yumei Liu¹

Affiliation

¹ Institute of Dermatology, Guangzhou Medical University, Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou, People's Republic of China.

^# Contributed equally.

Abstract

Knuckle pads (KPs) are benign hyperkeratotic fibrous thickening skin disorder characterized by nodules or plaques located on the extensor surface of the joints. However, there are no specific treatments for KPs so far. Here, we reported a case of KPs successfully treated with 2% crisaborole ointment combined with triamcinolone acetonide and neomycin plaster. This combined therapy might be a new therapeutic option for KPs.

Keywords: PDE-4 inhibitors; crisaborole; emerging therapy; knuckle pads; primary.

Publication types

Case Reports

Grants and funding

This study was supported by the Guangzhou Health Science and Technology Pro-ject (grant number 20211A011067) and the Science and Technology Planning Project of Guangzhou (grant number 201904010082).