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Temporal evolution of mechanical stimuli from vascular remodeling in response to the severity and duration of aortic coarctation in a preclinical model.
Azarnoosh J, Ghorbannia A, Ibrahim EH, Jurkiewicz H, Kalvin L, LaDisa JF Jr. Azarnoosh J, et al. Sci Rep. 2023 May 23;13(1):8352. doi: 10.1038/s41598-023-34400-8. Sci Rep. 2023. PMID: 37221191 Free PMC article.
Rabbits were exposed to CoA resulting in peak-to-peak blood pressure gradient (BPG(pp)) severities of 10, 10-20, and 20 mmHg for a duration of ~ 1, 3, or 20 weeks using permanent, dissolvable, and rapidly dissolvable sutures. Elastic moduli and thickness were estimated fro …
Rabbits were exposed to CoA resulting in peak-to-peak blood pressure gradient (BPG(pp)) severities of 10, 10-20, and 20 mmHg for a duration …