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VISTA drives macrophages towards a pro-tumoral phenotype that promotes cancer cell phagocytosis yet down-regulates T cell responses.
Exp Hematol Oncol. 2024 Mar 29;13(1):35. doi: 10.1186/s40164-024-00501-x.
Exp Hematol Oncol. 2024.
PMID: 38553748
Free PMC article.
CD24 Is a Potential Immunotherapeutic Target for Mantle Cell Lymphoma.
Freile JÁ, Ustyanovska Avtenyuk N, Corrales MG, Lourens HJ, Huls G, van Meerten T, Cendrowicz E, Bremer E.
Freile JÁ, et al.
Biomedicines. 2022 May 19;10(5):1175. doi: 10.3390/biomedicines10051175.
Biomedicines. 2022.
PMID: 35625912
Free PMC article.
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Tumor infiltrating CD8/CD103/TIM-3-expressing lymphocytes in epithelial ovarian cancer co-express CXCL13 and associate with improved survival.
Vlaming M, Bilemjian V, Freile JÁ, Melo V, Plat A, Huls G, Nijman HW, de Bruyn M, Bremer E.
Vlaming M, et al. Among authors: freile ja.
Front Immunol. 2022 Oct 21;13:1031746. doi: 10.3389/fimmu.2022.1031746. eCollection 2022.
Front Immunol. 2022.
PMID: 36341460
Free PMC article.
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The Novel Immune Checkpoint GPR56 Is Expressed on Tumor-Infiltrating Lymphocytes and Selectively Upregulated upon TCR Signaling.
Bilemjian V, Vlaming MR, Álvarez Freile J, Huls G, De Bruyn M, Bremer E.
Bilemjian V, et al. Among authors: alvarez freile j.
Cancers (Basel). 2022 Jun 28;14(13):3164. doi: 10.3390/cancers14133164.
Cancers (Basel). 2022.
PMID: 35804934
Free PMC article.
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A luminescence-based method to assess antigen presentation and antigen-specific T cell responses for in vitro screening of immunomodulatory checkpoints and therapeutics.
Álvarez Freile J, Qi Y, Jacob L, Lobo MF, Lourens HJ, Huls G, Bremer E.
Álvarez Freile J, et al.
Front Immunol. 2023 Jul 25;14:1233113. doi: 10.3389/fimmu.2023.1233113. eCollection 2023.
Front Immunol. 2023.
PMID: 37559730
Free PMC article.
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CD20 positive CD8 T cells are a unique and transcriptionally-distinct subset of T cells with distinct transmigration properties.
Vlaming M, Bilemjian V, Freile JÁ, Lourens HJ, van Rooij N, Huls G, van Meerten T, de Bruyn M, Bremer E.
Vlaming M, et al. Among authors: freile ja.
Sci Rep. 2021 Oct 15;11(1):20499. doi: 10.1038/s41598-021-00007-0.
Sci Rep. 2021.
PMID: 34654826
Free PMC article.
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