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Kaixin Jieyu Granule attenuates neuroinflammation-induced depressive-like behavior through TLR4/PI3K/AKT/FOXO1 pathway: a study of network pharmacology and experimental validation.
Xu M, Zhai W, Zhang Y, Pan J, Li J, Huang S. Xu M, et al. BMC Complement Med Ther. 2023 May 12;23(1):156. doi: 10.1186/s12906-023-03970-5. BMC Complement Med Ther. 2023. PMID: 37173696 Free PMC article.
BACKGROUND: Kaixin Jieyu Granule (KJG), an improved formula of Kai-xin-san and Si-ni-san, is a highly effective formula with demonstrated efficacy in preventing depression in previous studies. ...
BACKGROUND: Kaixin Jieyu Granule (KJG), an improved formula of Kai-xin-san and Si-ni-san, is a highly effective formula with demonstr …
Mechanism underlying the protective effect of Kaixin Jieyu Fang on vascular depression following cerebral white matter damage.
Zhang Y, Huang S, Wang Y, Pan J, Zheng J, Zhang X, Chen Y, Li D. Zhang Y, et al. Neural Regen Res. 2014 Jan 1;9(1):61-8. doi: 10.4103/1673-5374.125331. Neural Regen Res. 2014. PMID: 25206744 Free PMC article.
The Chinese compound Kaixin Jieyu Fang can be used to treat vascular depression; however, the underlying mechanism remains unclear. ...These results indicate that Kaixin Jieyu Fang can alleviate cerebral white matter damage, and the underlying mechanism is associate …
The Chinese compound Kaixin Jieyu Fang can be used to treat vascular depression; however, the underlying mechanism remains unclear. . …
Bushen Jieyu Tiaochong Formula reduces apoptosis of granulosa cells via the PERK-ATF4-CHOP signaling pathway in a rat model of polycystic ovary syndrome with chronic stress.
Pan X, Liu Y, Liu L, Pang B, Sun Z, Guan S, Yan Q, Mo T, Chen R, Xu M, Chang Z, Zhou X. Pan X, et al. J Ethnopharmacol. 2022 Jun 28;292:114923. doi: 10.1016/j.jep.2021.114923. Epub 2021 Dec 17. J Ethnopharmacol. 2022. PMID: 34923086
Adverse psychological stress can aggravate the occurrence and development of PCOS. Bushen Jieyu Tiaochong Formula (BJTF), a prescription of Traditional Chinese Medicine (TCM), has been used in the treatment of PCOS and shown to be effective in reducing negative emotion. .. …
Adverse psychological stress can aggravate the occurrence and development of PCOS. Bushen Jieyu Tiaochong Formula (BJTF), a prescript …
Effects of Kaixin Jieyu Decoction () on behavior, monoamine neurotransmitter levels, and serotonin receptor subtype expression in the brain of a rat depression model.
Huang SJ, Zhang XH, Wang YY, Pan JH, Cui HM, Fang SP, Wu W, Zheng J, Li DJ, Bai G. Huang SJ, et al. Chin J Integr Med. 2014 Apr;20(4):280-5. doi: 10.1007/s11655-014-1343-0. Epub 2014 Feb 24. Chin J Integr Med. 2014. PMID: 24567255
OBJECTIVE: To determine the mechanisms underlying the anti-depressant effects of Kaixin Jieyu Decoction (, KJD) by investigating the effects of KJD on behavior, monoamine neurotransmitter levels, and serotonin (5-HT) receptor subtype expression in the brain in a rat model …
OBJECTIVE: To determine the mechanisms underlying the anti-depressant effects of Kaixin Jieyu Decoction (, KJD) by investigating the …
Effects of kaixin jieyu decoction on behavior and glial fibrillary acidic protein expression in cerebral hippocampus of a rat vascular depression model.
Zhang XH, Huang SJ, Wang YY, Zhang Y, Pan JH, Zheng J, Li DJ, Lei XM. Zhang XH, et al. Chin J Integr Med. 2015 Mar;21(3):223-8. doi: 10.1007/s11655-014-1820-8. Epub 2014 Aug 6. Chin J Integr Med. 2015. PMID: 25098258
OBJECTIVE: To explore the effects and anti-depression mechanisms of Kaixin Jieyu Decoction (, KJD). METHODS: The rat vascular depression (VD) model was established by ligation of bilateral common carotid arteries (LBCCA) combined with chronic unpredictable mild stress (CUM …
OBJECTIVE: To explore the effects and anti-depression mechanisms of Kaixin Jieyu Decoction (, KJD). METHODS: The rat vascular depress …