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Page 1
STING inhibitors target the cyclic dinucleotide binding pocket.
Hong Z, Mei J, Li C, Bai G, Maimaiti M, Hu H, Yu W, Sun L, Zhang L, Cheng D, Liao Y, Li S, You Y, Sun H, Huang J, Liu X, Lieberman J, Wang C. Hong Z, et al. Among authors: mei j. Proc Natl Acad Sci U S A. 2021 Jun 15;118(24):e2105465118. doi: 10.1073/pnas.2105465118. Proc Natl Acad Sci U S A. 2021. PMID: 34099558 Free PMC article.
STING signaling in islet macrophages impairs insulin secretion in obesity.
Hong Z, Chen S, Sun J, Cheng D, Guo H, Mei J, Zhang X, Maimaiti M, Hao H, Cao P, Hu H, Wang C. Hong Z, et al. Among authors: mei j. Sci China Life Sci. 2024 Feb;67(2):345-359. doi: 10.1007/s11427-022-2371-9. Epub 2023 Oct 25. Sci China Life Sci. 2024. PMID: 37906411
The Cyclopeptide Astin C Specifically Inhibits the Innate Immune CDN Sensor STING.
Li S, Hong Z, Wang Z, Li F, Mei J, Huang L, Lou X, Zhao S, Song L, Chen W, Wang Q, Liu H, Cai Y, Yu H, Xu H, Zeng G, Wang Q, Zhu J, Liu X, Tan N, Wang C. Li S, et al. Among authors: mei j. Cell Rep. 2018 Dec 18;25(12):3405-3421.e7. doi: 10.1016/j.celrep.2018.11.097. Cell Rep. 2018. PMID: 30566866 Free article.