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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 1
1989 2
1992 2
1993 1
1996 1
1997 4
1998 6
1999 4
2000 4
2001 6
2002 12
2003 16
2004 16
2005 15
2006 23
2007 23
2008 26
2009 31
2010 51
2011 60
2012 108
2013 96
2014 98
2015 139
2016 128
2017 119
2018 133
2019 120
2020 154
2021 192
2022 227
2023 194
2024 90

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1,879 results

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Page 1
CD11c(+) microglia promote white matter repair after ischemic stroke.
Jia J, Zheng L, Ye L, Chen J, Shu S, Xu S, Bao X, Xia S, Liu R, Xu Y, Zhang M. Jia J, et al. Cell Death Dis. 2023 Feb 24;14(2):156. doi: 10.1038/s41419-023-05689-0. Cell Death Dis. 2023. PMID: 36828819 Free PMC article.
Ischemic stroke leads to white matter damage and neurological deficits. However, the characteristics of white matter injury and repair after stroke are unclear. ...These findings suggest that spontaneous white matter repair occurs after ischemic stroke, while …
Ischemic stroke leads to white matter damage and neurological deficits. However, the characteristics of white matter injury an …
Thermogenic adipocyte-derived zinc promotes sympathetic innervation in male mice.
Jiang J, Zhou D, Zhang A, Yu W, Du L, Yuan H, Zhang C, Wang Z, Jia X, Zhang ZN, Luan B. Jiang J, et al. Nat Metab. 2023 Mar;5(3):481-494. doi: 10.1038/s42255-023-00751-9. Epub 2023 Mar 6. Nat Metab. 2023. PMID: 36879120
Here, we identify primary zinc ion (Zn) as a thermogenic adipocyte-secreted factor that promotes sympathetic innervation and thermogenesis in brown adipose tissue and subcutaneous white adipose tissue in male mice. Depleting thermogenic adipocytes or antagonizing beta(3)-a …
Here, we identify primary zinc ion (Zn) as a thermogenic adipocyte-secreted factor that promotes sympathetic innervation and thermogenesis i …
Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.
Zhang Y, Yao Y, Xu Y, Li L, Gong Y, Zhang K, Zhang M, Guan Y, Chang L, Xia X, Li L, Jia S, Zeng Q. Zhang Y, et al. Nat Commun. 2021 Jan 4;12(1):11. doi: 10.1038/s41467-020-20162-8. Nat Commun. 2021. PMID: 33397889 Free PMC article.
Here, we design a ctDNA-based study of over 10,000 pan-cancer Chinese patients. Using parallel sequencing between plasma and white blood cells, 14% of plasma cell-free DNA samples contain clonal hematopoiesis (CH) variants, for which detectability increases with age. ...
Here, we design a ctDNA-based study of over 10,000 pan-cancer Chinese patients. Using parallel sequencing between plasma and white bl …
Growth arrest specific protein 6 alleviated white matter injury after experimental ischemic stroke.
Jia J, Xu S, Hu J, Gan Y, Sun M, Xia S, Bao X, Zhang M, Xu Y. Jia J, et al. J Cereb Blood Flow Metab. 2024 Jan;44(1):77-93. doi: 10.1177/0271678X231205078. Epub 2023 Oct 5. J Cereb Blood Flow Metab. 2024. PMID: 37794790
Ischemic white matter injury leads to long-term neurological deficits and lacks effective medication. ...Generally, we concluded that Gas6 cleared myelin debris and promoted cholesterol transportation protein expression through activating RXR, which could be one critical m …
Ischemic white matter injury leads to long-term neurological deficits and lacks effective medication. ...Generally, we concluded that …
aMAP risk score predicts hepatocellular carcinoma development in patients with chronic hepatitis.
Fan R, Papatheodoridis G, Sun J, Innes H, Toyoda H, Xie Q, Mo S, Sypsa V, Guha IN, Kumada T, Niu J, Dalekos G, Yasuda S, Barnes E, Lian J, Suri V, Idilman R, Barclay ST, Dou X, Berg T, Hayes PC, Flaherty JF, Zhou Y, Zhang Z, Buti M, Hutchinson SJ, Guo Y, Calleja JL, Lin L, Zhao L, Chen Y, Janssen HLA, Zhu C, Shi L, Tang X, Gaggar A, Wei L, Jia J, Irving WL, Johnson PJ, Lampertico P, Hou J. Fan R, et al. J Hepatol. 2020 Dec;73(6):1368-1378. doi: 10.1016/j.jhep.2020.07.025. Epub 2020 Jul 21. J Hepatol. 2020. PMID: 32707225 Free article.
Hepatic Acat2 overexpression promotes systemic cholesterol metabolism and adipose lipid metabolism in mice.
Ma Z, Huang Z, Zhang C, Liu X, Zhang J, Shu H, Ma Y, Liu Z, Feng Y, Chen X, Kuang S, Zhang Y, Jia Z. Ma Z, et al. Diabetologia. 2023 Feb;66(2):390-405. doi: 10.1007/s00125-022-05829-9. Epub 2022 Nov 15. Diabetologia. 2023. PMID: 36378328 Free PMC article.
In addition, the overexpression of Acat2 inhibited fatty acid, glucose and ketone metabolic pathways but promoted cholesterol metabolism and changed the bile acid pool and composition of the liver. Hepatic Acat2 overexpression also decreased the size of white adipocytes an …
In addition, the overexpression of Acat2 inhibited fatty acid, glucose and ketone metabolic pathways but promoted cholesterol metabolism and …
The metabolic ER stress sensor IRE1α suppresses alternative activation of macrophages and impairs energy expenditure in obesity.
Shan B, Wang X, Wu Y, Xu C, Xia Z, Dai J, Shao M, Zhao F, He S, Yang L, Zhang M, Nan F, Li J, Liu J, Liu J, Jia W, Qiu Y, Song B, Han JJ, Rui L, Duan SZ, Liu Y. Shan B, et al. Nat Immunol. 2017 May;18(5):519-529. doi: 10.1038/ni.3709. Epub 2017 Mar 27. Nat Immunol. 2017. PMID: 28346409
Myeloid-specific IRE1alpha abrogation in Ern1(f/f); Lyz2-Cre mice largely reversed high-fat diet (HFD)-induced M1-M2 imbalance in white adipose tissue (WAT) and blocked HFD-induced obesity, insulin resistance, hyperlipidemia and hepatic steatosis. ...
Myeloid-specific IRE1alpha abrogation in Ern1(f/f); Lyz2-Cre mice largely reversed high-fat diet (HFD)-induced M1-M2 imbalance in white …
Increased functional connectivity of white-matter in myotonic dystrophy type 1.
Li J, Li J, Huang P, Huang LN, Ding QG, Zhan L, Li M, Zhang J, Zhang H, Cheng L, Li H, Liu DQ, Zhou HY, Jia XZ. Li J, et al. Front Neurosci. 2022 Aug 1;16:953742. doi: 10.3389/fnins.2022.953742. eCollection 2022. Front Neurosci. 2022. PMID: 35979335 Free PMC article.
Although structural measurements showed that DM1 is predominantly associated with white-matter damage, they failed to reveal the dysfunction of the white-matter. ...Partial correlation analyzes were performed between the altered white-matter FC and clinical M …
Although structural measurements showed that DM1 is predominantly associated with white-matter damage, they failed to reveal the dysf …
Effect of corticosubcortical iron deposition on dysfunction in CADASIL is mediated by white matter microstructural damage.
Jia X, Li Y, Ying Y, Jia X, Tang W, Bian Y, Zhang J, Wang DJJ, Cheng X, Yang Q. Jia X, et al. Neuroimage Clin. 2023;39:103485. doi: 10.1016/j.nicl.2023.103485. Epub 2023 Jul 27. Neuroimage Clin. 2023. PMID: 37542975 Free PMC article.
However, the underlying pathophysiological mechanisms remain incompletely understood. Whether white matter microstructural changes mediate these processes is largely unclear. ...Mediation effect analysis was performed to explore the interrelationship between iron depositio …
However, the underlying pathophysiological mechanisms remain incompletely understood. Whether white matter microstructural changes me …
Aberrant White Matter Microstructure in Depressed Patients with Suicidality.
Zhang H, Li H, Yin L, Chen Z, Wu B, Huang X, Jia Z, Gong Q. Zhang H, et al. J Magn Reson Imaging. 2022 Apr;55(4):1141-1150. doi: 10.1002/jmri.27927. Epub 2021 Sep 22. J Magn Reson Imaging. 2022. PMID: 34549480
BACKGROUND: Depression is a common psychiatric disorder affecting 264 million people globally, and the worst outcome is suicide. While regional brain alterations in depressed suicidal brain have previously been reported, knowledge about white matter (WM) microstruct …
BACKGROUND: Depression is a common psychiatric disorder affecting 264 million people globally, and the worst outcome is suicide. Whil …
1,879 results