In this study, reconstruction of flame chemiluminescence distribution with complicated structure was numerically investigated and experimentally validated. The ill-conditioned equations were constructed using the quasi-Monte Carlo method and solved by an algebraic reconstruction technique, where the convergence criterion was the Euclidean norm of the dimensionless displacement vector. Results of a phantom study revealed that the number of camera angles is the main restriction on reconstruction accuracy, and increase of the flame's nonhomogeneity improves the sensibility of reconstruction accuracy to image resolution. Results of experimental reconstruction showed the CH* distribution in a Meker burner flame. This work provides a better understanding in how to establish experimental systems for complicated flame reconstruction.